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mitotic DNA integrity checkpoint

Known as: mitotic cell cycle G2/M transition decatenation checkpoint, topo II checkpoint, topoisomerase II checkpoint 
A mitotic cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

DNA integrity checkpointMitotic Cell Cycle

Narrower (1)

signal transduction involved in mitotic DNA integrity checkpoint

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Monitoring the DNA Topoisomerase II Checkpoint in Saccharomyces cerevisiae.
Topoisomerase II activity is crucial to maintain genome stability through the removal of catenanes in the DNA formed during DNA… 
2015
2015
4,6-Substituted-1,3,5-triazin-2(1H)-ones as monocyclic catalytic inhibitors of human DNA topoisomerase IIα targeting the ATP binding site.
2011
2011
Topoisomerase II: Characterization of the Topoisomerase II Checkpoint and the Classic top2-4 mutant allele
University of Minnesota Ph.D. dissertation. August 2011. Major: Molecular, Cellular, Developmental Biology and Genetics. Advisor… 
2006
2006
A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin.
Topoisomerase II (Topo II) performs topological modifications on double-stranded DNA molecules that are essential for chromosome… 
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