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midbrain development

Known as: mesencephalon development 
The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (1)

brain development

Narrower (4)

midbrain dopaminergic neuron differentiationmidbrain morphogenesissubstantia nigra developmentventral tegmental area development

Papers overview

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Highly Cited
2010
Highly Cited
2010
Effects of silver nanoparticles on the development and histopathology biomarkers of Japanese medaka (Oryzias latipes) using the partial-life test.
Highly Cited
2008
Highly Cited
2008
Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development
Prospective midbrain and cerebellum formation are coordinated by FGF ligands produced by the isthmic organizer. Previous studies… 
Review
2007
Review
2007
Genetics of septo-optic dysplasia
Septo-optic dysplasia (SOD) is a highly heterogeneous condition comprising a variable phenotype of optic nerve hypoplasia… 
Highly Cited
2007
Highly Cited
2007
Pbx proteins cooperate with Engrailed to pattern the midbrain-hindbrain and diencephalic-mesencephalic boundaries.
Highly Cited
2003
Highly Cited
2003
FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors
Early patterning of the vertebrate midbrain and cerebellum is regulated by a mid/hindbrain organizer that produces three… 
Highly Cited
2001
Highly Cited
2001
Sonic Hedgehog Control of Size and Shape in Midbrain Pattern Formation
Little is known about how patterns of cell types are organized to form brain structures of appropriate size and shape. To study… 
Highly Cited
2000
Highly Cited
2000
Involvement of fibroblast growth factor (FGF)18-FGF8 signaling in specification of left-right asymmetry and brain and limb development of the chick embryo
Highly Cited
1999
Highly Cited
1999
Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain.
Experiments involving tissue recombinations have implicated both early vertical and later planar signals in the specification and… 
Highly Cited
1996
Highly Cited
1996
Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development
A SECRETED signalling molecule encoded by the Wnt-1 gene is required for development of the central nervous system. In mouse… 
Highly Cited
1992
Highly Cited
1992
The midbrain-hindbrain phenotype of Wnt-1− Wnt-1− mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum
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