microprocessor complex

Known as: microprocessor complex location 
A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2017
012319892017

Papers overview

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2016
2016
During microRNA (miRNA) biogenesis, the Microprocessor complex (MC), composed minimally of Drosha, an RNaseIII enzyme, and DGCR8… (More)
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2015
2015
MicroRNAs (miRNAs) have been shown to play important roles in diverse cellular processes and linked to variety of disorders… (More)
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2014
2014
ARF is a multifunctional tumor suppressor that acts as both a sensor of oncogenic stimuli and as a key regulator of ribosome… (More)
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2013
2013
TDP-43 (TAR DNA-binding protein 43) is an RNA-binding protein implicated in RNA metabolism at several levels. Even if… (More)
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2013
2013
UNLABELLED MicroRNAs (miRNAs) have recently been shown to play fundamental roles in diverse cellular processes and linked to… (More)
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Highly Cited
2012
Highly Cited
2012
MicroRNAs (miRNAs) are noncoding RNAs that function as key posttranscriptional regulators of gene expression. miRNA maturation is… (More)
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2012
2012
The microprocessor complex mediates intranuclear biogenesis of precursor microRNAs from the primary microRNA transcript… (More)
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2011
2011
MicroRNAs (miRNA) are endogenous, short, non-coding RNA that undergo a multistep biogenesis before generating the functional… (More)
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Highly Cited
2009
Highly Cited
2009
MicroRNAs play important roles in animal development. Numerous conditional knockout (cKO) studies of Dicer have been performed to… (More)
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Review
2008
Review
2008
Encoded in the genome of most eukaryotes, microRNAs (miRNAs) have been proposed to regulate specifically up to 90% of human genes… (More)
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