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Control of nematode parasite infections relies largely on anthelmintic drugs, several of which act on nicotinic ACh receptors… Expand Three pharmacological subtypes of cholinergic receptors have been distinguished in Ascaris suum using a muscle contraction assay… Expand The development of resistance to all chemotherapeutic agents increases and needs to be addressed. We are interested in resistance… Expand Twenty-five known anthelmintic compounds were evaluated in vitro against the highly motile exsheathed non-feeding third-stage of… Expand Clinical signs and lesions of levamisole toxicosis include: nausea, vomiting, increased salivation, frequent urination and… Expand Rats can be solidly immunized against Trichinella spiralis by a series of methyridine-terminated oral infections with T. spiralis… Expand Methyridine, tetramisole and pyrantel affect several cholinergic mechanisms. In the rabbit, methyridine and tetramisole cause… Expand Abstract The absorption of methyridine has been examined following oral, s.c. and i.p. dosing to sheep, calves and cows and… Expand Abstract The effect of methyridine administered subcutaneously upon the intestinal phase of Trichinella spiralis in mice has been… Expand Critical studies using mice infected experimentally with nematodes (Nematospiroides dubius, Nippostrongylus muris and Heterakis… Expand