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methylosome

Known as: 20S methylosome, 20S methyltransferase complex, 20S methyltransferase complex location 
A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Lead induces the up-regulation of the protein arginine methyltransferase 5 possibly by its promoter demethylation.
The studies on lead (Pb) exposure linking to epigenetic modulations are caused by its differential actions on global DNA… 
2018
2018
Aflatoxin-induced upregulation of protein arginine methyltransferase 5 is mediated by protein kinase C and extracellular signal-regulated kinase
Aflatoxins are fungal metabolites classified into four major groups such as B1, B2, G1, and G2. These natural aflatoxins are… 
2017
2017
Sulforaphane suppresses PRMT5/MEP50 function in epidermal squamous cell carcinoma leading to reduced tumor formation
Protein arginine methyltransferase 5 (PRMT5) cooperates with methylosome protein 50 (MEP50) to arginine methylate histone H3 and… 
2017
2017
Identification of candidate substrates of ubiquitin-specific protease 13 using 2D-DIGE
The present study aimed to identify candidate substrates of ubiquitin-specific protease (USP)13 using two-dimensional… 
2017
2017
Investigation of novel functions of myosin phosphatase and smoothelin-like 1 protein
2016
2016
TIS7 induces transcriptional cascade of methylosome components required for muscle differentiation
TPA Induced Sequence 7 acts as a transcriptional co-regulator controlling the expression of genes involved in differentiation of… 
2011
2011
The Exon Junction Complex Component Y14 Modulates the Activity of the Methylosome in Biogenesis of Spliceosomal Small Nuclear Ribonucleoproteins*
The RNA-binding protein Y14 heterodimerizes with Mago as the core of the exon junction complex during precursor mRNA splicing and… 
2011
2011
Monoallelic Deletion of NFKBIA in Glioblastoma : When Less Is More
Next, they performed microarray profiling of the co-cultured osteoblasts and found IL6, a proproliferative cytokine involved in… 
2011
2011
Abstract P255: Protein Arginine Methyltransferase 5 and Methylosome Protein 50, Novel Components of P300/gata4 Complex, Suppress Hypertrophic Gene Transcriptions in Cardiomyocytes
Introduction: One of intrinsic histone acetyltransferases (HAT), p300, serves as a coactivator of hypertrophy-responsive… 
2011
2011
Abstract 15041: Protein Arginine Methyltransferase 5 and Methylosome Protein 50 Suppresses Hypertrophic Responses in Cardiomyocytes by Inhibition of p300/GATA4 Pathway
Introduction: One of the intrinsic histone acetyltransferases, p300, serves as a coactivator of hypertrophy-responsive… 
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