methoxyamine

Known as: O-methylhydroxylamine, methoxylamine 
An orally bioavailable small molecule inhibitor with potential adjuvant activity. Methoxyamine covalently binds to apurinic/apyrimidinic (AP) DNA… (More)
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Nondestructive Sampling of Living Systems Using in Vivo Solid-Phase Microextraction Gangfeng Ouyang,* Dajana Vuckovic, and Janusz… (More)
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2007
2007
PURPOSE Methoxyamine has been shown to potentiate the cytotoxic effect of temozolomide both in vitro and in human tumor xenograft… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE To improve the treatment of women with ovarian cancer, we are investigating the modulation of a prominent DNA-damaging… (More)
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2006
2006
We previously reported that methoxyamine (an inhibitor of base excision repair) potentiates iododeoxyuridine (IUdR)-induced… (More)
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2005
2005
Farnesyltransferase inhibitors (FTIs) are currently under investigation for leukemia treatment. We evaluated the FTI manumycin A… (More)
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2001
2001
We have previously shown that human cancer cells deficient in DNA mismatch repair (MMR) are resistant to the chemotherapeutic… (More)
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Highly Cited
1999
Highly Cited
1999
Previously we showed that a mismatch repair (MMR)-deficient cell line, HCT116 (hMLH1 mut), unlike a MMR wild-type cell line… (More)
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1988
1988
Incubated slices of young rat cerebellum were used to examine the possible relationship between the neurotoxic effects of… (More)
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1985
1985
This paper describes the use of methoxyamine to study the enzymatic reactions catalyzed by uracil-DNA glycosylase and by AP… (More)
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1983
1983
The Mn-catalase of Lactobacillus plantarum was inactivated when exposed to NH2OH plus H2O2, an effect which was not reversed by… (More)
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