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merodantoin

Known as: 1,3-dibutyl-2-thioxo-4,5-imidazolidinedione, N,N'-dibutyl-2-thio-4,5-imidazolidion 
National Institutes of Health

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2 relations

Broader (1)

Ethylenethiourea
analogs & derivatives

Papers overview

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1995
1995
Correlation between DNA topoisomerase II activity and cytotoxicity in pMC540 and merodantoin sensitive and resistant human breast cancer cells.
We have shown previously that preactivated merocyanine 540 (pMC540) and merodantoin appear to mediate their cytotoxic effects via… 
1995
1995
Growth inhibitory effects of pMC540 and merodantoin on established MCF-7 human breast tumor xenografts.
The effect of preactivated merocyanine 540 (pMC540) and one of its chemically synthesized active isolate merodantoin on… 
1995
1995
Relationship of mitochondrial function and cellular adenosine triphosphate levels to pMC540 and merodantoin cytotoxicity in MCF-7 human breast cancer cells.
In previous studies we have reported that preactivated merocyanine 540 (pMC540) and its chemically synthesized isolates merocil… 
1994
1994
Topoisomerase ll-dependent novel antitumor compounds merocil and merodantoin induce apoptosis in Daudi cells
Three photoproducts of merocyanlne 540 have been Isolated, chemically characterized and synthesized. Two of these photoproducts… 
1994
1994
In vitro and in vivo growth suppression of MCF‐7 human breast cancer by novel photoproducts and tamoxifen
Background. Preactivation is a novel photochemical method for the production of chemotherapeutic compounds that exert their… 
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