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meprin A complex

Known as: PABA peptide hydrolase complex, PABA peptide hydrolase complex location, meprin A complex location 
A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has… Expand
National Institutes of Health

Papers overview

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2018
2018
Pulmonary arterial hypertension (PAH) is a rare disease characterized by increased pulmonary pressure and vascular remodelling as… Expand
2015
2015
Human meprin β (h-meprin β), a single-zinc metalloendoprotease of the astacin family, is potentially involved in disorders such… Expand
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2014
2014
Background: Meprin metalloproteinases are implicated in the pathogenesis of inflammatory diseases where the cytokine IL-6 plays a… Expand
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2014
2014
Zinc metalloproteinases meprin α and meprin β are implicated in a variety of diseases, such as fibrosis, inflammation and… Expand
Review
2013
Review
2013
Meprin A, composed of α- and β-subunits, is a membrane-associated neutral metalloendoprotease that belongs to the astacin family… Expand
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Highly Cited
2012
Highly Cited
2012
Ectodomain shedding at the cell surface is a major mechanism to regulate the extracellular and circulatory concentration or the… Expand
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2009
2009
Meprin is a member of the astacin family of zinc metalloendopeptidases. It is widely distributed in the body, and hydrolyzes and… Expand
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2003
2003
The protease domains of the evolutionarily related α and β subunits of meprin metalloproteases are ∼55% identical at the amino… Expand
Highly Cited
1998
Highly Cited
1998
We examined the effect of meprin A, the major matrix degrading metalloproteinase in rat kidney, on the laminin-nidogen complex. N… Expand
1991
1991
Meprin-a is a metalloendopeptidase present at high levels in the kidney brush border of some inbred mouse strains. Meprin-b is a… Expand