menthofuran

 
National Institutes of Health

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2012
2012
Nicotine is the primary addictive agent in tobacco products and is metabolized in humans by CYP2A6. Decreased CYP2A6 activity has… (More)
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Highly Cited
2001
Highly Cited
2001
Peppermint (Mentha x piperita L.) was independently transformed with a homologous sense version of the 1-deoxy-d-xylulose-5… (More)
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2001
2001
(+)-Menthofuran is an undesirable monoterpenoid component of peppermint (Mentha x piperita) essential oil that is derived from… (More)
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1999
1999
(R)-(+)-Pulegone, a monoterpene constituent of pennyroyal oil, is a hepatotoxin that has been used in folklore medicine as an… (More)
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1998
1998
(R)-(+)-Menthofuran is a potent, mechanism-based inactivator of human liver cytochrome P450 (CYP or P450) 2A6. Menthofuran caused… (More)
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1992
1992
Menthofuran, a naturally occurring hepatotoxin, is metabolically activated to chemically reactive intermediates that are capable… (More)
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1992
1992
Metabolic fate of menthofuran (II) in rats was investigated. Menthofuran (II) was administered orally (200 mg/kg of the body… (More)
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1990
1990
Pulegone, a monoterpene that protects source plants against predators, is a hepatotoxic constituent of the folklore abortifacient… (More)
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1990
1990
Incubation of R-(+)-pulegone(I) with PB-induced rat liver microsomes in the presence of NADPH resulted in the formation of… (More)
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1987
1987
(R)-(+)-Pulegone, the major monoterpene component of the abortifacient mint oil, pennyroyal oil, is metabolized by hepatic… (More)
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