memoquin
National Institutes of Health
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Alzheimer's disease (AD) is characterized by progressive loss of cognitive function, dementia and altered behavior. Over 30…
Eight monomeric congeners, related to the multitarget lead candidate memoquin, were prepared and evaluated at multiple targets to…
The multifunctional nature of Alzheimer's disease (AD) provides the logical foundation for the development of an innovative drug…
Novel multitargeted antioxidants 3-6 were designed by combining the antioxidant features, namely, a benzoquinone fragment and a…
The initial transition of amyloid β (1–42) (Aβ42) soluble monomers/small oligomers from unordered/α‐helix to a β‐sheet‐rich…
One of the characteristics of Alzheimer's disease (AD) that hinders the discovery of effective disease-modifying therapies is the…