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memoquin

National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Alzheimer's disease (AD) is characterized by progressive loss of cognitive function, dementia and altered behavior. Over 30… Expand
Review
2011
Review
2011
SummaryAlzheimer’s disease is currently thought to be a complex, multifactorial syndrome, unlikely to arise from a single causal… Expand
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2011
2011
Eight monomeric congeners, related to the multitarget lead candidate memoquin, were prepared and evaluated at multiple targets to… Expand
Highly Cited
2011
Highly Cited
2011
Lipoic acid (LA) is a natural antioxidant. Its structure was previously combined with that of the acetylcholinesterase inhibitor… Expand
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Highly Cited
2011
Highly Cited
2011
Memoquin (1) is a lead compound multitargeted against Alzheimer's disease (AD). It is an AChE inhibitor, free-radical scavenger… Expand
Review
2009
Review
2009
The multifunctional nature of Alzheimer's disease (AD) provides the logical foundation for the development of an innovative drug… Expand
Highly Cited
2009
Highly Cited
2009
Novel multitargeted antioxidants 3-6 were designed by combining the antioxidant features, namely, a benzoquinone fragment and a… Expand
2009
2009
The present article expands on the study of structure-activity relationships of the novel class of quinone-bearing polyamines, as… Expand
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Highly Cited
2007
Highly Cited
2007
The initial transition of amyloid β (1–42) (Aβ42) soluble monomers/small oligomers from unordered/α‐helix to a β‐sheet‐rich… Expand
Highly Cited
2007
Highly Cited
2007
One of the characteristics of Alzheimer's disease (AD) that hinders the discovery of effective disease-modifying therapies is the… Expand