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mebeverine
Known as:
4-(ethyl-(4-methoxy-alpha-methylphenethyl)aminobutyl) veratrate
, duspatalin
, spasmotalin
Â
Â
National Institutes of Health
Topic mentions per year
Topic mentions per year
1963-2017
0
5
10
1963
2017
Related topics
Related topics
4 relations
Broader (3)
Anticonvulsants
Parasympatholytics
Phenethylamines
Narrower (1)
Mebeverine hydrochloride
Related mentions per year
Related mentions per year
1940-2018
1940
1960
1980
2000
2020
mebeverine
Anticonvulsants
Phenethylamines
Parasympatholytics
Mebeverine hydrochloride
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Efficacy of ramosetron in the treatment of male patients with irritable bowel syndrome with diarrhea: a multicenter, randomized clinical trial, compared with mebeverine.
K. J. Lee
,
N. Y. Kim
,
+10 authors
Poong Lyul Rhee
Neurogastroenterology and motility : the official…
2011
BACKGROUND The 5-HT(3) receptor antagonists are known to be effective for the treatment of diarrhea-predominant irritable bowel…Â
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2009
2009
pH-Sensitive Mebeverine Microspheres for Colon Delivery
Phanchaxari M Dandagi
,
Vinayak Shivamurthy Mastiholimath
,
Andanappa Gadad
,
Aniruddha Kulkarni
,
B. K. Konnur
Indian journal of pharmaceutical sciences
2009
Mebeverine hydrochloride is known to suffer from extensive first pass effect. In an attempt to improve its oral bioavailability…Â
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2006
2006
Investigative implications of the instability and metabolism of mebeverine.
Simon Elliott
,
Victoria J. Burgess
Journal of analytical toxicology
2006
The anti-spasmodic drug mebeverine is used in the treatment of irritable bowel syndrome. It has been found to be unstable and…Â
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2005
2005
Cognitive behaviour therapy in addition to antispasmodic treatment for irritable bowel syndrome in primary care: randomised controlled trial.
Tom Kennedy
,
Roger Jones
,
Simon Darnley
,
Paul Seed
,
Simon Charles Wessely
,
Trudie Chalder
BMJ
2005
OBJECTIVE To assess the efficacy of cognitive behaviour therapy delivered in primary care for treating irritable bowel syndrome…Â
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2004
2004
Treatment patterns and health care costs of mebeverine-treated IBS patients: a case-control study.
Wim G. Goettsch
,
Guido van den Boom
,
Nancy S Breekveldt-Postma
,
André J. P. M. Smout
,
Ron M. C. Herings
Pharmacoepidemiology and drug safety
2004
BACKGROUND Irritable bowel syndrome (IBS) is a functional disorder affecting the quality of life of patients. In the Netherlands…Â
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2002
2002
Identification of mebeverine acid as the main circulating metabolite of mebeverine in man.
Arnel Stockis
,
P. J. M. Guelen
,
Dirk E De Vos
Journal of pharmaceutical and biomedical analysis
2002
The intestinal spasmolytic drug mebeverine is known to undergo fast in vivo enzymatic hydrolysis into mebeverine alcohol and…Â
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1999
1999
Alosetron relieves pain and improves bowel function compared with mebeverine in female nonconstipated irritable bowel syndrome patients.
R. H. Jones
,
Gerald Holtmann
,
+4 authors
John Mills
Alimentary pharmacology & therapeutics
1999
BACKGROUND Irritable bowel syndrome is one of the most common gastrointestinal disorders, yet no therapy convincingly controls…Â
(More)
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1996
1996
Mebeverine alters small bowel motility in irritable bowel syndrome.
P. R. Evans
,
Y T Bak
,
John E. Kellow
Alimentary pharmacology & therapeutics
1996
BACKGROUND AND AIM Despite its widespread use in irritable bowel syndrome (IBS), limited clinical data exist on the effects of…Â
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1991
1991
Facile hydrolysis of mebeverine in vitro and in vivo: negligible circulating concentrations of the drug after oral administration.
Rachel Dickinson
,
Polly Baker
,
Morris Emory Franklin
,
Wayne D. Hooper
Journal of pharmaceutical sciences
1991
The HPLC methods for the determination of plasma concentrations of the antispasmodic agent mebeverine (0.01-10 micrograms/mL) and…Â
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1986
1986
Comparison of the therapeutic effect of wheat bran, mebeverine and placebo in patients with the irritable bowel syndrome.
Werner Kruis
,
Marlene Weinzierl
,
Peter Schuessler
,
Jane Holl
Digestion
1986
There is no generally accepted treatment in the irritable bowel syndrome (IBS), probably because of a lack of convincing…Â
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