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meayamycin B
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Morpholines
Pyrans
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Total synthesis of meayamycin B.
Robert K. Bressin
,
S. Osman
,
I. Pohorilets
,
U. Basu
,
K. Koide
The Journal of organic chemistry
2020
Corpus ID: 212677632
Meayamycin B is currently the most potent modulator of the splicing factor 3b subunit 1 and used by dozens of research groups…
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2019
2019
Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma
R. Sciarrillo
,
A. Wojtuszkiewicz
,
+16 authors
E. Giovannetti
EBioMedicine
2019
Corpus ID: 58604347
Introduction Therapeutic options for diffuse malignant peritoneal mesothelioma (DMPM) are limited to surgery and locoregional…
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2015
2015
An siRNA Screen Identifies the U2 snRNP Spliceosome as a Host Restriction Factor for Recombinant Adeno-associated Viruses
Claire A. Schreiber
,
T. Sakuma
,
+7 authors
Y. Ikeda
PLoS pathogens
2015
Corpus ID: 25791877
Adeno-associated viruses (AAV) have evolved to exploit the dynamic reorganization of host cell machinery during co-infection by…
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2014
2014
Regulation of HPV16 E6 and MCL1 by SF3B1 inhibitor in head and neck cancer cells
Y. Gao
,
S. Trivedi
,
R. Ferris
,
K. Koide
Scientific reports
2014
Corpus ID: 24902474
ABT-737 inhibits the anti-apoptotic proteins B-cell lymphoma 2 (BCL-2) and BCL-XL. Meayamycin B switches the splicing pattern of…
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2014
2014
Spliceosome Inhibitor Meayamycin B As a Novel Potential Chemotherapeutic Agent in ALL and AML
A. Wojtuszkiewicz
,
Y. Assaraf
,
+7 authors
J. Cloos
2014
Corpus ID: 208426182
Introduction The process of pre-mRNA splicing is gaining attention as a contributor to anticancer drug resistance and as a…
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2014
2014
Regulation of HPV 16 E 6 and MCL 1 by SF 3 B 1 inhibitor in head and neck cancer cells
Y. Gao
,
S. Trivedi
,
R. Ferris
,
K. Koide
2014
Corpus ID: 32101765
ABT-737 inhibits the anti-apoptotic proteins B-cell lymphoma 2 (BCL-2) and BCL-XL. Meayamycin B switches the splicing pattern of…
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Highly Cited
2013
Highly Cited
2013
Chemical perturbation of Mcl-1 pre-mRNA splicing to induce apoptosis in cancer cells.
Y. Gao
,
K. Koide
ACS chemical biology
2013
Corpus ID: 39500388
The myeloid cell leukemia-1 (MCL1) gene encodes antiapoptotic Mcl-1(L) and proapoptotic Mcl-1(S) proteins. In cancer, the Mcl-1(L…
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2013
2013
Abstract 2064: SF3B1 inhibitors sensitize head and neck squamous cell carcinoma to Bcl-xL inhibition by regulating Mcl-1 alternative splicing.
Y. Gao
2013
Corpus ID: 71361369
This study explored the application of the alternative splicing of Bcl-2 family protein Mcl-1 in combination chemotherapy for…
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