mature B cell differentiation

Known as: mature B lymphocyte differentiation, mature B-cell differentiation, mature B-lymphocyte differentiation 
The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen. [GOC:jal, ISBN:0781735149]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
0119952017

Papers overview

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2015
2015
Splenic transitional B-cells (T1 and T2) are selected to avoid self-reactivity and to safeguard against autoimmunity, then… (More)
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2014
2014
The AIOLOS gene is important in the control of mature B-lymphocyte differentiation and proliferation. Previous research has shown… (More)
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2013
2013
Mantle cell lymphoma (MCL) is one of the most aggressive lymphoid neoplasms whose pathogenesis is not fully understood. The… (More)
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2011
2011
Chronic lymphocytic leukemia (CLL) is characterized by a clonal accumulation of mature neoplastic B cells that are resistant to… (More)
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2010
2010
Chromosome 11q21-qter is a very gene-rich region and is often targeted by genomic aberrations in a variety of human cancers… (More)
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Highly Cited
2009
Highly Cited
2009
Mature B-cell differentiation provides an important mechanism for the acquisition of adaptive immunity. Malignancies derived from… (More)
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2005
2005
B cells can differentiate into antibody-secreting plasma cells, however the signals that control the entry into this pathway are… (More)
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2003
2003
The tissue-specific transcriptional coactivator OCA-B is required for antigen-dependent B cell differentiation events, including… (More)
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Highly Cited
2002
Highly Cited
2002
RBP-J is a key mediator of Notch signaling that regulates cell fate determination in various lineages. To investigate the… (More)
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Highly Cited
2000
Highly Cited
2000
Seventy percent of peripheral immature conventional (B2) B cells fail to develop into mature B cells. The nature of this cell… (More)
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