FAQ

mature B cell differentiation

Known as: mature B lymphocyte differentiation, mature B-cell differentiation, mature B-lymphocyte differentiation 
The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen. [GOC:jal, ISBN:0781735149]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
0119952017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Distinct Transcriptomic Features are Associated with Transitional and Mature B-Cell Populations in the Mouse Spleen
Splenic transitional B-cells (T1 and T2) are selected to avoid self-reactivity and to safeguard against autoimmunity, then… (More)
Is this relevant?
2014
2014
Overexpression of AIOLOS inhibits cell proliferation and suppresses apoptosis in Nalm-6 cells.
The AIOLOS gene is important in the control of mature B-lymphocyte differentiation and proliferation. Previous research has shown… (More)
Is this relevant?
2013
2013
SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma.
Mantle cell lymphoma (MCL) is one of the most aggressive lymphoid neoplasms whose pathogenesis is not fully understood. The… (More)
Is this relevant?
2011
2011
Deregulation of Aiolos expression in chronic lymphocytic leukemia is associated with epigenetic modifications.
Chronic lymphocytic leukemia (CLL) is characterized by a clonal accumulation of mature neoplastic B cells that are resistant to… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2010
2010
Serotonin receptor 3A expression in normal and neoplastic B cells.
Chromosome 11q21-qter is a very gene-rich region and is often targeted by genomic aberrations in a variety of human cancers… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Patterns of microRNA expression characterize stages of human B-cell differentiation.
Mature B-cell differentiation provides an important mechanism for the acquisition of adaptive immunity. Malignancies derived from… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2005
2005
CD72-mediated suppression of human naive B cell differentiation by down-regulating X-box binding protein 1.
B cells can differentiate into antibody-secreting plasma cells, however the signals that control the entry into this pathway are… (More)
Is this relevant?
2003
2003
Identification of transcription coactivator OCA-B-dependent genes involved in antigen-dependent B cell differentiation by cDNA array analyses.
The tissue-specific transcriptional coactivator OCA-B is required for antigen-dependent B cell differentiation events, including… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Notch–RBP-J signaling is involved in cell fate determination of marginal zone B cells
RBP-J is a key mediator of Notch signaling that regulates cell fate determination in various lineages. To investigate the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
A B-cell receptor-specific selection step governs immature to mature B cell differentiation.
Seventy percent of peripheral immature conventional (B2) B cells fail to develop into mature B cells. The nature of this cell… (More)
Is this relevant?