matrine, (5beta)-isomer

Known as: sophoridine 
 
National Institutes of Health

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matrine

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2014
2014
Synthesis and biological evaluation of sophoridinol derivatives as a novel family of potential anticancer agents.
New N-substituted sophoridinic acid/ester and sophoridinol derivatives were synthesized and evaluated for their cytotoxic… (More)
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2011
2011
In vitro anti-tumour activities of quinolizidine alkaloids derived from Sophora flavescens Ait.
The dry root of Sophora flavescens Ait. (SF) has long been used in a variety of Chinese herbal formulations to treat patients… (More)
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2010
2010
Preparation and In vitro Evaluation of Ethosomal Total Alkaloids of Sophora alopecuroides Loaded by a Transmembrane pH-Gradient Method
A novel transmembrane pH gradient active loading method to prepare alkaloids binary ethosomes was developed in this work. Using… (More)
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2009
2009
Comparative effects of sophocarpine and sophoridine on hERG K+ channel.
Human ether-à-go-go-related gene (hERG) has an important role in the repolarization of the cardiac action potential. Sophocarpine… (More)
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2008
2008
Sophocarpine and matrine inhibit the production of TNF-alpha and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice.
The present study aims to access the effects of sophora alkaloids on the production of pro-inflammatory cytokines and evaluate… (More)
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2007
2007
LC-MS characterization of efficacy substances in serum of experimental animals treated with Sophora flavescens extracts.
Anti-DHBV (duck hepatitis B virus) activity was found in the aqueous extracts of Sophora flavescens Ait. in vivo. Liquid… (More)
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2006
2006
Separation and determination of strychnine and brucine in Strychnos nux-vomica L. and its preparation by nonaqueous capillary electrophoresis.
An easy, rapid method for simultaneous determination of strychnine and brucine in Strychnos nux-vomica L. and its preparation was… (More)
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2006
2006
Antiviral effects of sophoridine against coxsackievirus B3 and its pharmacokinetics in rats.
Coxsackievirus B3 (CVB3) is a major pathogen for acute and chronic viral myocarditis. The aim of this study was to investigate… (More)
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2000
2000
Quinolizidine alkaloids from Sophora alopecuroides.
A new matrine-type alkaloid, 7alpha-hydroxysophoramine (1), was isolated from the aerial parts of Sophora alopecuroides together… (More)
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1999
1999
Determination of quinolizidine alkaloids in traditional Chinese herbal drugs by nonaqueous capillary electrophoresis.
A rapid method for the determination of quinolizidine alkaloids by nonaqueous capillary electrophoresis was developed. A total of… (More)
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