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maropitant citrate

Known as: (2S,3S)-N-(5-(1,1-Dimethylethyl)-2-methoxybenzyl)-2-(diphenylmethyl)-1-azabicyclo(2.2.2)octan-3-amine 2-hydroxy-1,2,3-propanetricarboxylate (1:1), Monohydrate, 2-benzhydryl-N-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine citrate monohydrate 
A neurokinin receptor antagonist with antiemetic activity. This agent is approved for veterinary use only.
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (2)

CJ-11,972Cerenia

Broader (1)

maropitant
maropitant 24 MG Oral Tablet [Cerenia]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study
BackgroundNausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to… 
Review
2017
Review
2017
Spotlight on the perioperative use of maropitant citrate
Neurokinin-1 (NK-1) receptors are present in both the central nervous system and peripheral tissues. Substance P (SP) is the… 
Review
2015
Review
2015
Nausea: current knowledge of mechanisms, measurement and clinical impact.
2014
2014
Effects of maropitant, acepromazine, and electroacupuncture on vomiting associated with administration of morphine in dogs.
OBJECTIVE To evaluate effects of maropitant, acepromazine, and electroacupuncture on morphine-related signs of nausea and… 
2014
2014
Effects of Maropitant Citrate or Acepromazine on the Incidence of Adverse Events Associated with Hydromorphone Premedication in Dogs
Background Vomiting is a common complication associated with the use of hydromorphine for pre‐emptive analgesia in dogs. The… 
2014
2014
Gastrointestinal toxicity after vincristine or cyclophosphamide administered with or without maropitant in dogs: a prospective randomised controlled study.
OBJECTIVES To assess the prevalence of gastrointestinal toxicity in dogs receiving chemotherapy with vincristine and… 
2014
2014
Efficacy of orally administered maropitant citrate in preventing vomiting associated with hydromorphone administration in dogs.
  • B. H. Hay Kraus
  • Journal of the American Veterinary Medical…
  • 2014
  • Corpus ID: 36036615
OBJECTIVE To evaluate the effectiveness of orally administered maropitant citrate in preventing vomiting after hydromorphone… 
2013
2013
The pharmacokinetics of maropitant citrate dosed orally to dogs at 2 mg/kg and 8 mg/kg once daily for 14 days consecutive days.
The pharmacokinetics of maropitant were evaluated in beagle dogs dosed orally with Cerenia® tablets (Pfizer Animal Health) once… 
2011
2011
Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background.
Murine ulcerative dermatitis (UD) is a common progressive condition of mice with a C57BL/6 background. Typically, mice present… 
Review
2010
Review
2010
Neurokinin-1 receptor antagonists: a comprehensive patent survey
Importance of the field: Substance P is involved in mediating a number of biological effects such as emesis, pain, inflammation… 
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