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maropitant citrate
Known as:
(2S,3S)-N-(5-(1,1-Dimethylethyl)-2-methoxybenzyl)-2-(diphenylmethyl)-1-azabicyclo(2.2.2)octan-3-amine 2-hydroxy-1,2,3-propanetricarboxylate (1:1), Monohydrate
, 2-benzhydryl-N-(5-tert-butyl-2-methoxybenzyl)quinuclidin-3-amine citrate monohydrate
A neurokinin receptor antagonist with antiemetic activity. This agent is approved for veterinary use only.
National Institutes of Health
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Related topics
Related topics
4 relations
Narrower (2)
CJ-11,972
Cerenia
Broader (1)
maropitant
maropitant 24 MG Oral Tablet [Cerenia]
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study
H. Kenward
,
J. Elliott
,
Terry Lee
,
L. Pelligand
BMC Veterinary Research
2017
Corpus ID: 29840391
BackgroundNausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to…
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Review
2017
Review
2017
Spotlight on the perioperative use of maropitant citrate
B. H. Hay Kraus
Veterinary medicine
2017
Corpus ID: 50782057
Neurokinin-1 (NK-1) receptors are present in both the central nervous system and peripheral tissues. Substance P (SP) is the…
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Review
2015
Review
2015
Nausea: current knowledge of mechanisms, measurement and clinical impact.
H. Kenward
,
L. Pelligand
,
K. Savary-Bataille
,
J. Elliott
The Veterinary Journal
2015
Corpus ID: 205516302
2014
2014
Effects of maropitant, acepromazine, and electroacupuncture on vomiting associated with administration of morphine in dogs.
R. Koh
,
N. Isaza
,
Huisheng Xie
,
K. Cooke
,
S. Robertson
Journal of the American Veterinary Medical…
2014
Corpus ID: 5388245
OBJECTIVE To evaluate effects of maropitant, acepromazine, and electroacupuncture on morphine-related signs of nausea and…
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2014
2014
Effects of Maropitant Citrate or Acepromazine on the Incidence of Adverse Events Associated with Hydromorphone Premedication in Dogs
A. Claude
,
A. Dedeaux
,
L. Chiavaccini
,
S. Hinz
Journal of Veterinary Internal Medicine
2014
Corpus ID: 8392785
Background Vomiting is a common complication associated with the use of hydromorphine for pre‐emptive analgesia in dogs. The…
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2014
2014
Gastrointestinal toxicity after vincristine or cyclophosphamide administered with or without maropitant in dogs: a prospective randomised controlled study.
S. Mason
,
I. Grant
,
J. Elliott
,
P. Cripps
,
L. Blackwood
Journal of Small Animal Practice
2014
Corpus ID: 32511515
OBJECTIVES To assess the prevalence of gastrointestinal toxicity in dogs receiving chemotherapy with vincristine and…
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2014
2014
Efficacy of orally administered maropitant citrate in preventing vomiting associated with hydromorphone administration in dogs.
B. H. Hay Kraus
Journal of the American Veterinary Medical…
2014
Corpus ID: 36036615
OBJECTIVE To evaluate the effectiveness of orally administered maropitant citrate in preventing vomiting after hydromorphone…
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2013
2013
The pharmacokinetics of maropitant citrate dosed orally to dogs at 2 mg/kg and 8 mg/kg once daily for 14 days consecutive days.
S. Lesman
,
J. Boucher
,
G. S. Grover
,
S. Cox
,
T. Bidgood
Journal of Veterinary Pharmacology and…
2013
Corpus ID: 41528488
The pharmacokinetics of maropitant were evaluated in beagle dogs dosed orally with Cerenia® tablets (Pfizer Animal Health) once…
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2011
2011
Maropitant citrate for treatment of ulcerative dermatitis in mice with a C57BL/6 background.
Misty J. Williams-Fritze
,
Jodi A Carlson Scholz
,
+4 authors
Peter C. Smith
Journal of the American Association for…
2011
Corpus ID: 2466211
Murine ulcerative dermatitis (UD) is a common progressive condition of mice with a C57BL/6 background. Typically, mice present…
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Review
2010
Review
2010
Neurokinin-1 receptor antagonists: a comprehensive patent survey
Shih-Chung Huang
,
V. Korlipara
Expert Opinion on Therapeutic Patents
2010
Corpus ID: 29192523
Importance of the field: Substance P is involved in mediating a number of biological effects such as emesis, pain, inflammation…
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