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mappicine
Known as:
7-(1-hydroxypropyl)-8-methylindolizino(1,2-b)quinolin-9(11H)-one
National Institutes of Health
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1 relation
Broader (1)
Alkaloids
Papers overview
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2009
2009
Synthesis, antioxidant, hemolytic and cytotoxicity activity of AB ring core of mappicine
S. Roopan
,
Fazlur Rahman
,
Nawaz Khan
2009
Corpus ID: 52226383
The series of AB ring cores of mappicine 5a-e were generated by the reaction of 2-chloroquinoline-3-carbaldehyde 4a-e with NaBH4…
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2003
2003
An efficient approach to 3,4-disubstituted pyridin-2-ones. Formal synthesis of mappicine ketone.
Ching-Han Lin
,
Min-Ruei Tsai
,
Yung S. Wang
,
N. Chang
Journal of Organic Chemistry
2003
Corpus ID: 12650353
Treatment of 3,4-dihydro-3-tosylpyridin-2-one 5 with sodium hydride and then alkyl halides gave various 3,4-disubstituted pyridin…
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Highly Cited
2002
Highly Cited
2002
Quasiracemic synthesis: concepts and implementation with a fluorous tagging strategy to make both enantiomers of pyridovericin and mappicine.
Qisheng Zhang
,
A. Rivkin
,
D. Curran
Journal of the American Chemical Society
2002
Corpus ID: 43811417
The concept of quasiracemic synthesis is introduced and illustrated with syntheses of both enantiomers of pyridovericin (whose…
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Highly Cited
2000
Highly Cited
2000
A concise formal total synthesis of mappicine and nothapodytine B via an intramolecular hetero Diels-Alder reaction.
M. Toyota
,
Chiyo Komori
,
Masataka Ihara
Journal of Organic Chemistry
2000
Corpus ID: 41629302
A six-step formal total synthesis of a natural alkaloid, mappicine (3), has been achieved. The highlight of our synthetic…
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2000
2000
New pyridone approach: total synthesis of mappicine ketone (nothapodytine B).
K. Mekouar
,
Y. Génisson
,
S. Leue
,
A. Greene
Journal of Organic Chemistry
2000
Corpus ID: 2868700
A novel synthesis of mappicine ketone, which possesses strong selective activity against the herpes viruses HSV-1 and HSV-2…
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2000
2000
Solution phase synthesis of libraries of polycyclic natural product analogues by cascade radical annulation: synthesis of a 64-member library of mappicine analogues and a 48-member library of…
Ó. de Frutos
,
D. Curran
Journal of combinatorial chemistry
2000
Corpus ID: 6120069
An improved cascade radical annulation route to (+/-)-mappicine, (S)-mappicine, and mappicine ketone is reported. The route is…
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2000
2000
Unprecedented adducts formed by camptothecin and mappicine ketone with maleic anhydride under microwave irradiation
B. Das
,
P. Madhusudhan
,
A. Kashinatham
2000
Corpus ID: 99909811
Camptothecin 11 is a naturally occurring novel pyrro lo-[3,4-b ]-quinoline alkaloid well-known for its potent antitumour activit…
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1998
1998
The first conversion of camptothecin to (S)-mappicine by an efficient chemoenzymatic method.
B. Das
,
P. Madhusudhan
,
A. Kashinatham
Bioorganic & Medicinal Chemistry Letters
1998
Corpus ID: 11337090
Highly Cited
1974
Highly Cited
1974
Mappicine, a minor alkaloid from Mappia foetida Miers.
T. R. Govindachari
,
K. R. Ravindranath
,
N. Viswanathan
Journal of The Chemical Society-perkin…
1974
Corpus ID: 30438946
The structure of mappicine, a minor alkaloid isolated from Mappia foetida Miers, has been established as (IIa){7-(1-hydroxypropyl…
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