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mappicine

Known as: 7-(1-hydroxypropyl)-8-methylindolizino(1,2-b)quinolin-9(11H)-one 
 
National Institutes of Health

Papers overview

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2009
2009
The series of AB ring cores of mappicine 5a-e were generated by the reaction of 2-chloroquinoline-3-carbaldehyde 4a-e with NaBH4… Expand
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2005
2005
Cascade radical cyclisation involving homolytic aromatic substitution has been used to synthesise new tetracycles. Treatment of… Expand
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2002
2002
Solution-phase mixture synthesis has efficiency advantages and favorable reaction kinetics. Applications of this technique… Expand
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2002
2002
The concept of quasiracemic synthesis is introduced and illustrated with syntheses of both enantiomers of pyridovericin (whose… Expand
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2002
2002
Ambient-temperature reactions of electron-rich aryl isonitriles with substituted 6-iodo-N-propargylpyridones in the presence of… Expand
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2000
2000
A six-step formal total synthesis of a natural alkaloid, mappicine (3), has been achieved. The highlight of our synthetic… Expand
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2000
2000
An improved cascade radical annulation route to (+/-)-mappicine, (S)-mappicine, and mappicine ketone is reported. The route is… Expand
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2000
2000
A novel synthesis of mappicine ketone, which possesses strong selective activity against the herpes viruses HSV-1 and HSV-2… Expand
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1998
1998
Camptothecin has been converted for the first time to (S)-mappicine via mappicine ketone, which is the sole product of the… Expand
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1974
1974
The structure of mappicine, a minor alkaloid isolated from Mappia foetida Miers, has been established as (IIa){7-(1-hydroxypropyl… Expand
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