mappicine

Known as: 7-(1-hydroxypropyl)-8-methylindolizino(1,2-b)quinolin-9(11H)-one 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2004
02419972004

Papers overview

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2005
2005
Cascade radical cyclisation involving homolytic aromatic substitution has been used to synthesise new tetracycles. Treatment of… (More)
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2003
2003
Enamides 5, on treatment with Bu(3)SnH-AIBN, underwent aryl radical cyclization in a 5-exo manner to give 1-[bis(phenylthio… (More)
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2002
2002
The concept of quasiracemic synthesis is introduced and illustrated with syntheses of both enantiomers of pyridovericin (whose… (More)
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2002
2002
Solution-phase mixture synthesis has efficiency advantages and favorable reaction kinetics. Applications of this technique… (More)
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2001
2001
The solution-phase synthesis of organic compounds as mixtures rather than in individual pure form offers efficiency advantages… (More)
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2000
2000
A six-step formal total synthesis of a natural alkaloid, mappicine (3), has been achieved. The highlight of our synthetic… (More)
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2000
2000
A novel synthesis of mappicine ketone, which possesses strong selective activity against the herpes viruses HSV-1 and HSV-2… (More)
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2000
2000
An improved cascade radical annulation route to (+/-)-mappicine, (S)-mappicine, and mappicine ketone is reported. The route is… (More)
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1998
1998
Camptothecin has been converted for the first time to (S)-mappicine via mappicine ketone, which is the sole product of the… (More)
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1997
1997
The photodegradation of irinotecan (CPT-11), the semi-synthetic derivative of the antitumor alkaloid 20(S)-camptothecin, has been… (More)
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