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National Institutes of Health
analogs & derivatives
Semantic Scholar uses AI to extract papers important to this topic.
Inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands. 2. 4-(2-Malonyl)phenylalanine as a potent phosphotyrosyl mimetic.
Journal of medicinal chemistry
Corpus ID: 9493025
Nonhydrolyzable phosphotyrosyl (pTyr) mimetics serve as important components of many competitive Grb2 SH2 domain inhibitors. To…
Mapping the subsite preferences of protein tyrosine phosphatase PTP-1B using combinatorial chemistry approaches.
Corpus ID: 2271396
Protein tyrosine phosphatases (PTPases) are important regulators of signal transduction systems, but the specificity of their…
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