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malate dehydrogenase (decarboxylating) activity

Known as: (S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating), 'malic' enzyme, (S)-malate:NAD+ oxidoreductase (decarboxylating) 
Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+. [EC:1.1.1.38, EC:1.1.1.39]
National Institutes of Health

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Malate dehydrogenase (decarboxylating)malate dehydrogenase (decarboxylating) (NADP+) activity

Papers overview

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1996
1996
Thyromimetic mode of action of peroxisome proliferators: activation of 'malic' enzyme gene transcription.
Peroxisome proliferators induce thyroid-hormone-dependent liver activities, e.g. 'malic' enzyme, mitochondrial glycerol-3… 
Highly Cited
1995
Highly Cited
1995
Effect of adrenaline and phorbol myristate acetate or bacterial lipopolysaccharide on stimulation of pathways of macrophage glucose, glutamine and O2 metabolism. Evidence for cyclic AMP-dependent…
Adrenaline has recently been shown to stimulate both glucose metabolism and H2O2 release by macrophages but the activity of the… 
1990
1990
Differential biogenesis of photosystem-II in mesophyll and bundle-sheath cells of 'malic' enzyme NADP(+)-type C4 plants. A comparative protein and RNA analysis.
We have investigated the photosystem-II organization in differentiating-bundle-sheath cells of the three malate dehydrogenase… 
1990
1990
The changes in hepatic enzyme expression caused by selenium deficiency and hypothyroidism in rats are produced by independent mechanisms.
Selenium (Se) deficiency for 5 weeks in rats produced changes in the activity of a number of hepatic, renal and plasma enzymes… 
Highly Cited
1980
Highly Cited
1980
Development of NADPH-producing pathways in rat heart.
The behaviours of the principal NADPH-producing enzymes (glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase… 
1979
1979
Two forms of 'malic' enzyme with different regulatory properties in Trypanosoma cruzi.
1. Cell-free extracts from culture epimastigotes of Trypanosoma cruzi contained two forms of NADP+-linked 'malic' enzyme (EC 1.1… 
Highly Cited
1976
Highly Cited
1976
Effects of thyroid hormone deficiency on the distribution of hepatic metabolites and control of pathways of carbohydrate metabolism in liver and adipose tissue of the rat.
1. Measurements have been made of the hepatic metabolites in normal and thyroidectomized rats and enzymes of the glycolytic route… 
Highly Cited
1975
Highly Cited
1975
Carbon dioxide fixation in trypanosomatids
Fixation of carbon dioxide has been demonstrated for extracts from Crithidia fasciculata, Trypanosoma mega and Trypanosoma brucei… 
1974
1974
Regulation of 'malic' enzyme of Solanum tuberosum by metabolites.
A purification of ;malic' enzyme from potato is described. The purified enzyme is specific for NADP and requires a bivalent… 
Highly Cited
1971
Highly Cited
1971
Isolation and properties of a 'malic' enzyme from cauliflower bud mitochondria.
1. A ;malic' enzyme [l-malate-NAD oxidoreductase (decarboxylating), EC 1.1.1.39] has been isolated from cauliflower bud… 
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