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mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response

Known as: unconventional splicing of XBP1 mRNA, XBP1 mRNA splicing, via endonucleolytic cleavage and ligation, UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response 
The spliceosome-independent cleavage and ligation of the mRNA encoding a UFP-specific transcription factor to remove a single intron, thereby… 
National Institutes of Health

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Broader (1)

IRE1-mediated unfolded protein response

Papers overview

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2013
2013
Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities
BackgroundThe Y-box protein-1 (YB-1) fulfills pleiotropic functions relating to gene transcription, mRNA processing, and… 
2011
2011
HSV-1 Cgal+ Infection Promotes Quaking RNA Binding Protein Production and Induces Nuclear-Cytoplasmic Shuttling of Quaking I-5 Isoform in Human Hepatoma Cells*
Herpesvirus type 1 (HSV-1) based oncolytic vectors arise as a promising therapeutic alternative for neoplastic diseases including… 
Highly Cited
2008
Highly Cited
2008
Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene
Objective UDP-glucuronosyltransferase 2B7 (UGT2B7) plays a central role in the liver-mediated biotransformation of endogenous and… 
Highly Cited
2006
Highly Cited
2006
Variants in the human insulin gene that affect pre-mRNA splicing: is -23HphI a functional single nucleotide polymorphism at IDDM2?
Predisposition to type 1 diabetes and juvenile obesity is influenced by the susceptibility locus IDDM2 that includes the insulin… 
Highly Cited
2004
Highly Cited
2004
Using chromatin immunoprecipitation to map cotranscriptional mRNA processing in Saccharomyces cerevisiae.
The chromatin immunoprecipitation (ChIP) technique has been used to determine where and under what conditions DNA binding… 
Highly Cited
2003
Highly Cited
2003
Mutations in the pre-mRNA splicing-factor genes PRPF3, PRPF8, and PRPF31 in Spanish families with autosomal dominant retinitis pigmentosa.
PURPOSE Mutations in the systemically expressed pre-mRNA splicing-factor genes PRPF3, PRPF8, and PRPF31 have recently been… 
2002
2002
Abnormal mRNA splicing resulting from consensus sequence splicing mutations of ATP7B
More than 200 Wilson disease (WD) disease‐causing mutations have been defined to date. Missense mutations are largely prevalent… 
1998
1998
Silent nucleotide substitution in the sterol 27-hydroxylase gene (CYP 27) leads to alternative pre-mRNA splicing by activating a cryptic 5' splice site at the mutant codon in cerebrotendinous…
A functionally silent nucleotide substitution of the sterol 27-hydroxylase gene (CYP 27), identified in two families with… 
Highly Cited
1991
Highly Cited
1991
The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNA.
We previously described an avian sarcoma-leukosis virus (ASLV) insertion mutation that causes a decrease in the ratio of… 
1984
1984
Site specific deletions of regulatory sequences in a ribosomal protein-RNA polymerase operon in Escherichia coli. Effects on beta and beta' gene expression.
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