Skip to search formSkip to main contentSkip to account menu

mRNA cleavage

Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner. [GOC:mah]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Construction of an M1GS Ribozyme for Targeted and Rapid mRNA Cleavage; Application on the Ets-2 Oncogene.
BACKGROUND RNase P-mediated cleavage of target RNAs has been proposed as a promising tool for gene silencing. Ets-2 proto… 
2018
2018
Detection of MicroRNA-Mediated Target mRNA Cleavage and 3'-Uridylation in Human Cells by a SLA-RT-PCR Analysis.
  • Jing LinL. Ji
  • Methods in molecular biology
  • 2018
  • Corpus ID: 54472574
MicroRNA (miRNA) plays an important role in posttranscriptional regulation of gene expression by dominantly binding to the 3'-UTR… 
2013
2013
A-Site mRNA Cleavage Is Not Required for tmRNA-Mediated ssrA-Peptide Tagging
In Escherichia coli, prolonged translational arrest allows mRNA degradation into the A site of stalled ribosomes. The enzyme that… 
2012
2012
Identification of Inverse Regulator-a (Inr-a) as Synonymous with Pre-mRNA Cleavage Complex II Protein (Pcf11) in Drosophila
A common modulation of gene expression in aneuploids is an inverse correlation of the monitored gene with the dosage of another… 
2011
2011
The herpes simplex virus virion host shutoff protein is targeted to mRNA cleavage sites through interactions with components of the host translational apparatus
............................................................................................................................................. ii APPROVAL PAGE ................................................................................................................................ iv LIST OF ILLUSTRATIONS ................................................................................................................... vi LIST OF TABLES .................................................................................................................................... ix AKNOWLEDGEMENTS ........................................................................................................................ x Chapter 
2009
2009
A rapid and sensitive method to detect siRNA-mediated mRNA cleavage in vivo using 5′ RACE and a molecular beacon probe
Specific detection of mRNA cleavage by 5′RACE is the only method to confirm the knockdown of mRNA by RNA interference, but is… 
2005
2005
Translation of stable hepadnaviral mRNA cleavage fragments induced by the action of phosphorothioate-modified antisense oligodeoxynucleotides
Phosphorothioate-modified antisense oligodeoxynucleotides (ASOs) are used to suppress gene expression by inducing RNase H… 
2005
2005
Determination and Analysis of the Pre-mRNA Cleavage sites in Arabidopsis
Alignment of the Arabidopsis cDNA to genome DNA sequences revealed that approximately half of the mRNAs were found to contain a 3… 
2002
2002
Epstein-Barr virus nuclear antigen 5 inhibits pre-mRNA cleavage and polyadenylation.
The long-standing suspicion that Epstein-Barr virus nuclear antigen 5 (EBNA5) is involved in transcription regulation was… 
1990
1990
Effects of oligo sequence and chemistry on the efficiency of oligodeoxyribonucleotide-mediated mRNA cleavage.
Using the endogenous histone H4 mRNA of Xenopus oocytes as a target, we have previously shown that 20mer oligos complementary to… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)