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lymphoid enhancer-binding factor 1

Known as: Lymphoid Enhancer-Binding Factor 1 [Chemical/Ingredient], Transcription Factor, LEF-1, T Cell Specific Transcription Factor 1 alpha 
Lymphoid enhancer-binding factor 1 (399 aa, ~44 kDa) is encoded by the human LEF1 gene. This protein is involved in Wnt signaling and transcriptional… Expand
National Institutes of Health

Papers overview

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Highly Cited
2001
Highly Cited
2001
To understand how the Wnt coreceptor LRP-5 is involved in transducing the canonical Wnt signals, we identified Axin as a protein… Expand
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Highly Cited
1999
Highly Cited
1999
beta-Catenin plays a dual role in the cell: one in linking the cytoplasmic side of cadherin-mediated cell-cell contacts to the… Expand
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Highly Cited
1999
Highly Cited
1999
Members of the LEF-1/TCF family of transcription factors have been implicated in the transduction of Wnt signals. However… Expand
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Highly Cited
1996
Highly Cited
1996
THE cytoplasmic proteins β-catenin of vertebrates and armadillo of Drosophila have two functions: they link the cadherin cell… Expand
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Highly Cited
1996
Highly Cited
1996
The cytoplasmic proteins beta-catenin of vertebrates and armadillo of Drosophila have two functions: they link the cadherin cell… Expand
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Highly Cited
1996
Highly Cited
1996
XTcf-3 is a maternally expressed Xenopus homolog of the mammalian HMG box factors Tcf-1 and Lef-1. The N-terminus of XTcf-3 binds… Expand
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Highly Cited
1996
Highly Cited
1996
Vertebrate beta-catenin and Drosophila Armadillo share structural similarities suggesting that beta-catenin, like Armadillo, has… Expand
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Highly Cited
1995
Highly Cited
1995
T cell-specific transcription factor (TCF-1) and lymphoid enhancer factor 1 (LEF-1) have been implicated exclusively in the… Expand
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Highly Cited
1992
Highly Cited
1992
The high mobility group (HMG) domain is a DNA-binding motif that is associated with several eukaryotic regulatory proteins… Expand
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Highly Cited
1991
Highly Cited
1991
Lymphoid-specific cDNA clones were isolated that encode a nuclear protein with homology to the chromosomal nonhistone protein HMG… Expand
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