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loxtidine

National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Histamine H2 AntagonistsTriazoles

Narrower (1)

loxtidine hemisuccinate (1:1)

Papers overview

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1997
1997
Gastrin receptor expression and function during rapid transformation of the enterochromaffin-like cells in an African rodent
1996
1996
Somatostatin receptor regulation of gastric enterochromaffin-like cell transformation to gastric carcinoid.
1996
1996
DNA single-strand scission in the pyloric mucosa of rat stomach induced by four glandular stomach carcinogens and three other chemicals.
1995
1995
Are enterochromaffinlike cell tumours reversible? An experimental study on gastric carcinoids induced in Mastomys by histamine2-receptor blockade
1994
1994
Evaluation of the trophic effect of longterm treatment with the histamine H2 receptor antagonist loxtidine on rat oxyntic mucosa by differential counting of dispersed cells.
To evaluate whether the general trophic effect of gastrin on the oxyntic mucosa is an indirect effect mediated by histamine H2… 
1992
1992
Effects on the rat oxyntic mucosa of the histamine2‐antagonist loxtidine and the H+, K+‐ATPase inhibitor omepvazole
The present study examined whether histamine could affect the growth of the enterochromaffin‐like (ECL) cell and the parietal… 
Review
1991
Review
1991
Neuroendocrine cell hyperplasia and neuroendocrine carcinoma of the rodent fundic stomach.
1991
1991
Uptake of tritiated thymidine by cells of the rat gastric mucosa after exposure to loxtidine or omeprazole.
The H2-antagonist loxtidine and the H+/K(+)-ATPase inhibitor omeprazole inhibit gastric acid secretion and both have been… 
1988
1988
Investigations into the genotoxic potential of loxtidine, a long-acting H2-receptor antagonist.
Loxtidine, a potent, non-competitive histamine H2-receptor antagonist was evaluated for genotoxic potential using a range of… 
Highly Cited
1985
Highly Cited
1985
Pharmacological basis for the induction of gastric carcinoid tumours in the rat by loxtidine, an unsurmountable histamine H2‐receptor blocking drug
1 The very late occurrence of gastric carcinoids in a life‐span carcinogenicity study with loxtidine in the rat might have… 
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