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lortalamine

Known as: 4a,10-(Iminoethano)-4aH-(1)benzopyrano(3,2-c)pyridin-12-one, 8-chloro-1,2,3,4,10,10a-hexahydro-2-methyl-, (4aalpha,10alpha,10aalpha)-(+-)-, 4a-amino-8-chloro-2-methyl-1,2,3,4,4a,10a-hexahydro-10H-benzopyrano(3,2-c)pyridin-10-ylacetic acid lactam 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Benzopyrans

Papers overview

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2010
2010
Metabolism of the anti-depressant lortalamine
SummaryHumans excreted an oral dose of 5 mg of the anti-depressant lortalamine (radiolabelled with carbon-14) mainly in the urine… Expand
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Review
2006
Review
2006
PET imaging of norepinephrine transporters.
The involvement of the norepinephrine transporter (NET) in the pathophysiology and treatment of attention deficit hyperactivity… Expand
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Highly Cited
2005
Highly Cited
2005
Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3‐Cl‐[11C…
We have synthesized and evaluated several new ligands for imaging the norepinephrine transporter (NET) system in baboons with… Expand
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2005
2005
Synthesis and C-11 labeling of three potent norepinephrine transporter selective ligands ((R)-nisoxetine, lortalamine, and oxaprotiline) for comparative PET studies in baboons.
  • K. Lin, Y. Ding
  • Bioorganic & medicinal chemistry
  • 2005
    • Corpus ID: 6256713
Three potent antidepressants, (R)-nisoxetine, lortalamine, and oxaprotiline, with high affinity and high selectivity for the… Expand
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1990
1990
Ocular toxicity in beagle dogs with lortalamine, a non tricyclic antidepressant compound.
During a preclinical safety evaluation study, an indication of ocular toxicity was noted in beagle dogs receiving orally (gelatin… Expand
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1985
1985
Pharmacology of lortalamine, a new potent non-tricyclic antidepressant.
The new substance (+/-)8-chloro-1,2,3,4,10,10a-hexahydro-2-methyl-4a,10-(iminoethano )-4aH -[1]benzopyrano[3,2-c]pyridin-12-one… Expand
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