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lortalamine

Known as: 4a,10-(Iminoethano)-4aH-(1)benzopyrano(3,2-c)pyridin-12-one, 8-chloro-1,2,3,4,10,10a-hexahydro-2-methyl-, (4aalpha,10alpha,10aalpha)-(+-)-, 4a-amino-8-chloro-2-methyl-1,2,3,4,4a,10a-hexahydro-10H-benzopyrano(3,2-c)pyridin-10-ylacetic acid lactam 
National Institutes of Health

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1 relation

Broader (1)

Benzopyrans

Papers overview

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2010
2010
Metabolism of the anti-depressant lortalamine
SummaryHumans excreted an oral dose of 5 mg of the anti-depressant lortalamine (radiolabelled with carbon-14) mainly in the urine… 
Review
2006
Review
2006
PET imaging of norepinephrine transporters.
The involvement of the norepinephrine transporter (NET) in the pathophysiology and treatment of attention deficit hyperactivity… 
Highly Cited
2005
Highly Cited
2005
Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3‐Cl‐[11C…
We have synthesized and evaluated several new ligands for imaging the norepinephrine transporter (NET) system in baboons with… 
2005
2005
Synthesis and C-11 labeling of three potent norepinephrine transporter selective ligands ((R)-nisoxetine, lortalamine, and oxaprotiline) for comparative PET studies in baboons.
1990
1990
Ocular toxicity in beagle dogs with lortalamine, a non tricyclic antidepressant compound.
During a preclinical safety evaluation study, an indication of ocular toxicity was noted in beagle dogs receiving orally (gelatin… 
1985
1985
Pharmacology of lortalamine, a new potent non-tricyclic antidepressant.
The new substance (+/-)8-chloro-1,2,3,4,10,10a-hexahydro-2-methyl-4a,10-(iminoethano )-4aH -[1]benzopyrano[3,2-c]pyridin-12-one… 
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