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lomitapide

Known as: 9H-Fluorene-9-Carboxamide, N-(2,2,2-Trifluoroethyl)-9-(4-(4-(((4'-(Trifluoromethyl)(1,1'-Biphenyl)-2-yl)Carbonyl)Amino)-1-Piperidinyl)Butyl)-, N-(2,2,2-Trifluoroethyl)-9-(4-(4-(((4'-(Trifluoromethyl)Biphenyl-2-yl)Carbonyl)Amino)Piperidin-1-yl)Butyl)-9H-Fluorene-9-Carboxamide 
A small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible… 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Familial hypercholesterolemia (FH) is a common heritable condition in which mutations of genes governing cholesterol metabolism… 
Review
2017
Review
2017
BackgroundDespite extensive use of statins, patients with hypercholesterolemia, especially homozygous familial… 
Review
2016
Review
2016
Lipoprotein(a) [Lp(a)], a low‐density lipoprotein (LDL)‐like particle, has been independently associated with increased… 
Review
2013
Review
2013
Purpose of review Microsomal triglyceride transfer protein (MTP) is a key protein in the secretion of apolipoprotein B-containing… 
Review
2013
Review
2013
Purpose of review Lipid-lowering is an intervention that reduces atherosclerosis and its complications. Statins currently form…