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liver hypoxia

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
012319512017

Papers overview

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2014
2014
Role of Hypoxia Inducing Factor-1β in Alcohol-Induced Autophagy, Steatosis and Liver Injury in Mice
Chronic alcohol causes liver hypoxia and steatosis, which eventually develops into alcoholic liver disease (ALD). While it has… (More)
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2012
2012
Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis.
BACKGROUND Iron metabolism, regulated by the iron hormone hepcidin, and oxygen homeostasis, dependent on hypoxia-inducible… (More)
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2012
2012
HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice.
BACKGROUND & AIMS Chronic alcohol intake stimulates hepatic oxygen consumption and subsequently causes liver hypoxia, leading to… (More)
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Highly Cited
2011
Highly Cited
2011
Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice.
UNLABELLED Chronic alcohol causes hepatic steatosis and liver hypoxia. Hypoxia-regulated hypoxia-inducible factor 1-α, (HIF-1… (More)
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2009
2009
Pharmacological inhibition of integrin alphavbeta3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis.
UNLABELLED The vitronectin receptor integrin alphavbeta3 promotes angiogenesis by mediating migration and proliferation of… (More)
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2005
2005
Coagulation-mediated hypoxia and neutrophil-dependent hepatic injury in rats given lipopolysaccharide and ranitidine.
Idiosyncrasy-like liver injury occurs in rats cotreated with nonhepatotoxic doses of ranitidine (RAN) and bacterial… (More)
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2004
2004
Liver hypoxia and lack of recovery after reperfusion at high blood alcohol levels in the intragastric feeding model of alcohol liver disease.
The purpose of this study was to test for the presence of liver hypoxia and recovery after reperfusion when blood alcohol levels… (More)
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Highly Cited
2003
Highly Cited
2003
Hypoxic hepatitis: clinical and hemodynamic study in 142 consecutive cases.
The centrilobular liver cell necrosis observed in hypoxic hepatitis is generally attributed to failure of hepatic blood perfusion… (More)
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2003
2003
Tissue hypoxia during bacterial sepsis is attenuated by PR-39, an antibacterial peptide.
Endotoxin (a lipopolysaccharide (LPS) component of the Gram negative bacterial cell wall) induces sepsis in laboratory animals… (More)
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2002
2002
Endotoxin-induced liver hypoxia: defective oxygen delivery versus oxygen consumption.
In vivo EPR was used to investigate liver oxygenation in a hemodynamic model of septic shock in mice. Oxygen-sensitive material… (More)
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