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lipoate metabolic process

Known as: lipoate metabolism, lipoic acid metabolic process, lipoic acid metabolism 
The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid. [GOC:ai, ISBN:0198506732]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Progress in the Enzymology of the Mitochondrial Diseases of Lipoic Acid Requiring Enzymes
  • J. Cronan
  • Frontiers in Genetics
  • 2020
    • Corpus ID: 218755145
Three human mitochondrial diseases that directly affect lipoic acid metabolism result from heterozygous missense and nonsense… Expand
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2018
2018
Evaluation of the nutrition and function of cow and goat milk based on intestinal microbiota by metagenomic analysis.
Milk contains nutrients needed by the body, and the main components of different animal milk vary. Accordingly, we evaluated cow… Expand
2017
2017
Conditional knock-out of lipoic acid protein ligase 1 reveals redundancy pathway for lipoic acid metabolism in Plasmodium berghei malaria parasite
BackgroundLipoic acid is a cofactor for α-keto acid dehydrogenase system that is involved in the central energy metabolism. In… Expand
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Review
2016
Review
2016
Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway
  • J. Cronan
  • Microbiology and Molecular Reviews
  • 2016
    • Corpus ID: 206837555
SUMMARY Although the structure of lipoic acid and its role in bacterial metabolism were clear over 50 years ago, it is only in… Expand
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2014
2014
Mutations in the lipoyltransferase LIPT1 gene cause a fatal disease associated with a specific lipoylation defect of the 2-ketoacid dehydrogenase complexes.
Cofactor disorders of mitochondrial energy metabolism are a heterogeneous group of diseases with a wide variety of clinical… Expand
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2014
2014
Hipertensión pulmonar grave: forma de comienzo de un nuevo defecto del metabolismo del ácido lipoico
La hipertensión pulmonar (HTP) es una enfermedad grave e infrecuente. La causa más común en niños son las cardiopatı́as cong… Expand
2011
2011
A Complex Lipoate Utilization Pathway in Listeria monocytogenes*
Although a complete pathway of lipoic acid metabolism has been established in Escherichia coli, lipoic acid metabolism in other… Expand
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Review
2010
Review
2010
Lipoic Acid Metabolism in Microbial Pathogens
SUMMARY Lipoic acid [(R)-5-(1,2-dithiolan-3-yl)pentanoic acid] is an enzyme cofactor required for intermediate metabolism in free… Expand
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1994
1994
Mutants of Escherichia coli K-12 that are resistant to a selenium analog of lipoic acid identify unknown genes in lipoate metabolism.
Lipoic acid is a disulfide-containing cofactor required for the reactions catalyzed by alpha-ketoacid dehydrogenase enzyme… Expand
Highly Cited
1993
Highly Cited
1993
Lipoic acid metabolism in Escherichia coli: sequencing and functional characterization of the lipA and lipB genes.
Two genes, lipA and lipB, involved in lipoic acid biosynthesis or metabolism were characterized by DNA sequence analysis. The… Expand
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