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lipoate metabolic process
Known as:
lipoate metabolism
, lipoic acid metabolic process
, lipoic acid metabolism
The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid. [GOC:ai, ISBN:0198506732]
National Institutes of Health
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Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Progress in the Enzymology of the Mitochondrial Diseases of Lipoic Acid Requiring Enzymes
J. Cronan
Frontiers in Genetics
2020
Corpus ID: 218755145
Three human mitochondrial diseases that directly affect lipoic acid metabolism result from heterozygous missense and nonsense…
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2018
2018
Evaluation of the nutrition and function of cow and goat milk based on intestinal microbiota by metagenomic analysis.
Zhaoxia Wang
,
Shuaiming Jiang
,
+4 authors
Jiachao Zhang
Food & function
2018
Corpus ID: 4357725
Milk contains nutrients needed by the body, and the main components of different animal milk vary. Accordingly, we evaluated cow…
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2017
2017
Conditional knock-out of lipoic acid protein ligase 1 reveals redundancy pathway for lipoic acid metabolism in Plasmodium berghei malaria parasite
Min Wang
,
Qiong Wang
,
Xiang Gao
,
Z. Su
Parasites & Vectors
2017
Corpus ID: 3852099
BackgroundLipoic acid is a cofactor for α-keto acid dehydrogenase system that is involved in the central energy metabolism. In…
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Review
2016
Review
2016
Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway
J. Cronan
Microbiology and Molecular Reviews
2016
Corpus ID: 206837555
SUMMARY Although the structure of lipoic acid and its role in bacterial metabolism were clear over 50 years ago, it is only in…
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2014
2014
Mutations in the lipoyltransferase LIPT1 gene cause a fatal disease associated with a specific lipoylation defect of the 2-ketoacid dehydrogenase complexes.
F. Tort
,
Xènia Ferrer-Cortès
,
+12 authors
A. Ribes
Human molecular genetics
2014
Corpus ID: 10787070
Cofactor disorders of mitochondrial energy metabolism are a heterogeneous group of diseases with a wide variety of clinical…
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2014
2014
Hipertensión pulmonar grave: forma de comienzo de un nuevo defecto del metabolismo del ácido lipoico
A. L. Maseri
,
C. Castilla
,
J. L. M. Ybancos
,
Pilar Rodríguez-Pombo
2014
Corpus ID: 203732935
2011
2011
A Complex Lipoate Utilization Pathway in Listeria monocytogenes*
Quin H. Christensen
,
J. Hagar
,
M. O’Riordan
,
J. Cronan
The Journal of Biological Chemistry
2011
Corpus ID: 11721626
Although a complete pathway of lipoic acid metabolism has been established in Escherichia coli, lipoic acid metabolism in other…
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Review
2010
Review
2010
Lipoic Acid Metabolism in Microbial Pathogens
Maroya D. Spalding
,
S. Prigge
Microbiology and Molecular Biology Reviews
2010
Corpus ID: 34778441
SUMMARY Lipoic acid [(R)-5-(1,2-dithiolan-3-yl)pentanoic acid] is an enzyme cofactor required for intermediate metabolism in free…
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1994
1994
Mutants of Escherichia coli K-12 that are resistant to a selenium analog of lipoic acid identify unknown genes in lipoate metabolism.
K. Reed
,
T. Morris
,
J. Cronan
Proceedings of the National Academy of Sciences…
1994
Corpus ID: 25091694
Lipoic acid is a disulfide-containing cofactor required for the reactions catalyzed by alpha-ketoacid dehydrogenase enzyme…
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Highly Cited
1993
Highly Cited
1993
Lipoic acid metabolism in Escherichia coli: sequencing and functional characterization of the lipA and lipB genes
K. Reed
,
J. Cronan
Journal of bacteriology
1993
Corpus ID: 24460754
Two genes, lipA and lipB, involved in lipoic acid biosynthesis or metabolism were characterized by DNA sequence analysis. The…
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