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lingzhiol

 
National Institutes of Health

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Terpenes

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2019
2019
Eight-Step Enantiodivergent Synthesis of (+)- and (-)-Lingzhiol.
An eight-step enantioselective synthesis of lingzhiol is described herein. The sense of an asymmetric Michael reaction is… Expand
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2018
2018
Meroterpenoids from Ganoderma sinense protect hepatocytes and cardiomyocytes from oxidative stress induced injuries.
Four meroterpenoids, applanatumols F (1), H (3), I (2), and lingzhiol (4) were isolated from the 95% EtOH extract of the fruiting… Expand
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2017
2017
A Radical-Based Synthesis of Lingzhiol.
The polycyclic natural product lingzhiol [(±)-1] was synthesized from dimethoxytetralone 8 via cyclization of an intermediate… Expand
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2016
2016
Biogenetically Inspired Synthesis of Lingzhiol.
A concise stereo- and enantioselective synthesis of lingzhiol has been achieved featuring a biogenetically inspired Brønsted acid… Expand
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2016
2016
An approach to (±)-Lingzhiol.
(±)-Lingzhiol has been synthesized from commercially available 5,8-dimethoxytetralone in seven steps with an overall yield of 10… Expand
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2016
2016
Total Synthesis of Lingzhiol and Its Derivatives
 
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2016
2016
Biogenetically Inspired Total Synthesis of Lingzhiol. Design and Synthesis of Axially Chiral N-Heterocyclic Carbene Catalysts.
 
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2015
2015
Concise synthesis of (±)-Lingzhiol via epoxy-arene cyclization.
Concise synthesis of (±)-Lingzhiol has been achieved. The key reaction involves one-step construction of a 5/5/6/6 tetra-ring… Expand
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2013
2013
Lingzhiols, unprecedented rotary door-shaped meroterpenoids as potent and selective inhibitors of p-Smad3 from Ganoderma lucidum.
(+)-Lingzhiol and (-)-lingzhiol, a pair of rotary door-shaped meroterpenoidal enantiomers, were isolated from Ganoderma lucidum… Expand
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2013
2013
Lingzhiol A and application of lingzhiol A in drug production and foods
Glossy ganoderma as a traditional Chinese medicine is called immortal grass since ancient times and known as the ability to treat… Expand
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