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light chain disease

Known as: chain disease light, chain disease lights, Bence Jones Myeloma 
A condition in which plasma cells secrete immunoglobulin light chains of only one type, kappa or lambda. Light chain deposition disease is often… 
National Institutes of Health

Related topics

Related topics

22 relations
ArthritisAtypical lymphocyteB lymphoblastB-Lymphocytes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Light chain deposition disease of the kidney. Morphological aspects in 24 patients
Renal biopsies and autopsy specimens of 23 patients with light chain deposition disease (LCDD) and one with only heavy chain… 
2002
2002
CASE REPORT: Light Chain Deposition Disease of the Liver Without Renal Involvement in a Patient with Multiple Myeloma Related to Liver Failure and Rapid Fatal Outcome
We describe a 36-year-old man with advanced multiple myeloma (Salmon and Durie stage III) who developed jaundice and severe… 
1998
1998
κ light chain deposition disease of the liver
We report the case of a middle-aged woman presenting epigastric discomfort, hepatomegaly, biochemical signs of cholestasis, bone… 
Highly Cited
1997
Highly Cited
1997
Molecular modeling of immunoglobulin light chains implicates hydrophobic residues in non-amyloid light chain deposition disease.
Light chain deposition disease is a severe complication of certain immunoproliferative disorders, due to the secretion of a… 
1997
1997
Nodular pulmonary immunoglobulin light chain deposits with coexistent amyloid and nonamyloid features in an HIV-infected patient.
Isolated nodular pulmonary amyloidosis is a rare condition characterized by localized deposits of immunoglobulin (Ig) light chain… 
1997
1997
Amino‐terminal identity of co‐existent amyloid and non‐amyloid immunoglobulin κ light chain deposits. A human disease to study alterations of protein conformation
Tissue deposition of monoclonal immunoglobulin light chains is a serious complication in some patients with B cell proliferative… 
Review
1994
Review
1994
The fibrillary glomerulopathies.
1989
1989
Light chain deposition disease derived from the kappa I light chain subgroup. Biochemical characterization.
The authors biochemically analyzed the nonamyloidotic light chain deposits, the first studied in this way, from a patient with… 
Review
1979
Review
1979
An evaluation of diabetic and pseudodiabetic glomerulosclerosis.
Highly Cited
1976
Highly Cited
1976
Kappa and lambda light chain disease: survival rates and clinical manifestations
Ninety-seven patients with light chain disease (LCD) were studied. The median survival from diagnosis was 30 mo for 52 patients… 
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