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lidorestat

Known as: 3-((4,5,7-Triflurobenzothiazol-2-yl)methyl)-1H-indol-1-yl-acetic Acid, 3-((4,5,7-trifluorobenzothiazol-2-yl)methyl)indole-N-acetic acid 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

EML 676

Broader (2)

Indoleacetic AcidsThiazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Base promoted synthesis of novel indole-dithiocarbamate compounds as potential anti-inflammatory therapeutic agents for treatment of acute lung injury.
2018
2018
High glucose concentration suppresses a SIRT2 regulated pathway that enhances neurite outgrowth in cultured adult sensory neurons
2015
2015
Synthesis and pharmacological evaluation of a novel AT1 angiotensin II receptor antagonist with anti-hypertension and anti-tumor effects
Abstract A new compound 2-(4-((2-butyl-5-nitro-1H-benzo[d]imidazol-1-yl)methyl)-1H-indol-1-yl) benzamide (1) was designed… 
Review
2015
Review
2015
Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases.
Diabetes mellitus occurrence has been associated to the modification of the physiological levels of glucose and is often… 
2012
2012
Synthesis, anti-hypertensive effect of a novel angiotensin II AT1 receptor antagonist and its anti-tumor activity in prostate cancer.
Since the first non-peptide Ang II receptor antagonist was originally reported, it has become the most common target in the… 
2011
2011
Synthesis of Some Heterocyclic Compounds Derived from 1,3- dihydro-2H-indol-2-one
In this work (2-oxo-2,3-dihydro-1H-indol-1-yl)Acetic acid was prepared from (1,3-dihydro-2H-indol-2-one) with chloro acetic acid… 
2009
2009
Regulation of Plasma Fructose and Mortality in Mice by the Aldose Reductase Inhibitor Lidorestat
Aldose reductase (AR), an enzyme widely believed to be involved in the aberrant metabolism of glucose and development of diabetic… 
Highly Cited
2005
Highly Cited
2005
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic…
Recent efforts to identify treatments for chronic diabetic complications have resulted in the discovery of a novel series of… 
2005
2005
Derives d'acide indol-1-yl-acetique
L'invention concerne des derives d'acide indol-1-yl-acetique et leur utilisation comme principe actif dans l'elaboration de… 
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