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lidorestat
Known as:
3-((4,5,7-Triflurobenzothiazol-2-yl)methyl)-1H-indol-1-yl-acetic Acid
, 3-((4,5,7-trifluorobenzothiazol-2-yl)methyl)indole-N-acetic acid
National Institutes of Health
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Related topics
Related topics
3 relations
Narrower (1)
EML 676
Broader (2)
Indoleacetic Acids
Thiazoles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Base promoted synthesis of novel indole-dithiocarbamate compounds as potential anti-inflammatory therapeutic agents for treatment of acute lung injury.
Zengqiang Song
,
Yan Zhou
,
+9 authors
G. Liang
European journal of medicinal chemistry
2019
Corpus ID: 85514323
2018
2018
High glucose concentration suppresses a SIRT2 regulated pathway that enhances neurite outgrowth in cultured adult sensory neurons
E. Schartner
,
M. Sabbir
,
+4 authors
P. Fernyhough
Experimental Neurology
2018
Corpus ID: 51975463
2015
2015
Synthesis and pharmacological evaluation of a novel AT1 angiotensin II receptor antagonist with anti-hypertension and anti-tumor effects
Xiaolu Bao
,
Weibo Zhu
,
+6 authors
Zhilong Chen
Clinical and experimental hypertension
2015
Corpus ID: 485141
Abstract A new compound 2-(4-((2-butyl-5-nitro-1H-benzo[d]imidazol-1-yl)methyl)-1H-indol-1-yl) benzamide (1) was designed…
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Review
2015
Review
2015
Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases.
A. S. Grewal
,
Shashikant Bhardwaj
,
D. Pandita
,
V. Lather
,
B. S. Sekhon
Mini-Reviews in Medical Chemistry
2015
Corpus ID: 35121444
Diabetes mellitus occurrence has been associated to the modification of the physiological levels of glucose and is often…
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2012
2012
Synthesis, anti-hypertensive effect of a novel angiotensin II AT1 receptor antagonist and its anti-tumor activity in prostate cancer.
Ya-jing Da
,
W-D Yuan
,
Linfeng Zhu
,
Z-l Chen
Arzneimittel-Forschung
2012
Corpus ID: 24466551
Since the first non-peptide Ang II receptor antagonist was originally reported, it has become the most common target in the…
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2011
2011
Synthesis of Some Heterocyclic Compounds Derived from 1,3- dihydro-2H-indol-2-one
A. Nahida
2011
Corpus ID: 99140331
In this work (2-oxo-2,3-dihydro-1H-indol-1-yl)Acetic acid was prepared from (1,3-dihydro-2H-indol-2-one) with chloro acetic acid…
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2009
2009
Regulation of Plasma Fructose and Mortality in Mice by the Aldose Reductase Inhibitor Lidorestat
H. Noh
,
Yunying Hu
,
+5 authors
I. Goldberg
Journal of Pharmacology and Experimental…
2009
Corpus ID: 25579789
Aldose reductase (AR), an enzyme widely believed to be involved in the aberrant metabolism of glucose and development of diabetic…
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Highly Cited
2005
Highly Cited
2005
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic…
M. V. Van Zandt
,
Michael L. Jones
,
+9 authors
A. Podjarny
Journal of Medicinal Chemistry
2005
Corpus ID: 23795411
Recent efforts to identify treatments for chronic diabetic complications have resulted in the discovery of a novel series of…
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2005
2005
Derives d'acide indol-1-yl-acetique
A. Fecher
,
H. Fretz
,
K. Hilpert
,
M. Riederer
2005
Corpus ID: 188903124
L'invention concerne des derives d'acide indol-1-yl-acetique et leur utilisation comme principe actif dans l'elaboration de…
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