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licochalcone A

Known as: 3-dimethylallyl-4,4'-dihydroxy-6-methoxychalcone 
National Institutes of Health

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Chalcones

Papers overview

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2017
2017
Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry
AbstractThe metabolism of the chemoprevention agent licochalcone A, which is a chemopreventive chalcone found in abundance in the… 
2017
2017
Combining Chemical Profiling and Network Analysis to Investigate the Pharmacology of Complex Prescriptions in Traditional Chinese Medicine
We present a paradigm, combining chemical profiling, absorbed components detection in plasma and network analysis, for… 
2015
2015
Selective inhibition of liver X receptor α-mediated lipogenesis in primary hepatocytes by licochalcone A
BackgroundSterol regulatory element binding protein-1c (SREBP-1c) is a regulator of the lipogenic pathway and is… 
2014
2014
Effects of licochalcone A on the bioavailability and pharmacokinetics of nifedipine in rats: possible role of intestinal CYP3A4 and P‐gp inhibition by licochalcone A
The purpose of this study was to investigate the possible effects of licochalcone A (a herbal medicine) on the pharmacokinetics… 
2013
2013
Chemical analysis and anti-inflammatory comparison of the cell culture of Glycyrrhiza with its field cultivated variety.
2012
2012
Licochalcone A prevents adipocyte differentiation and lipogenesis via suppression of peroxisome proliferator-activated receptor γ and sterol regulatory element-binding protein pathways.
Licochalcone A (LA) has been shown to exert multiple pharmacological effects, including anti-inflammatory, antiparasitic… 
2009
2009
Licochalcone A bound to bovine serum albumin: a spectroscopic, photophysical and structural study
The interaction of Licochalcone A (LA) with bovine serum albumin (BSA) was studied by circular dichroism (CD), UV-Vis absorption… 
2008
2008
Structure and properties of licochalcone A-human serum albumin complexes in solution: a spectroscopic, photophysical and computational approach to understand drug-protein interaction.
In the present contribution we address the study of the interaction of a flavonoid-derivative licochalcone A (LA) with human… 
2008
2008
Anti-proliferative effect of licochalcone A on vascular smooth muscle cells.
Licochalcone A, a flavonoid found in licorice root (Glycyrrhiza glabra), is known for its anti-microbial activity and its… 
1997
1997
Synthesis, isolation and identification of glucuronides and mercapturic acids of a novel antiparasitic agent, licochalcone A.
1. Four glucuronic acid conjugates of licochalcone A (Lica), and their metabolites, have been synthesized using rabbit and pig… 
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