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lebein

 
National Institutes of Health

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Viper Venoms

Papers overview

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2017
2017
Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor‐induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression
Lebein, is an heterodimeric disintegrin isolated from Macrovipera lebetina snake venom that was previously characterized as an… Expand
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2016
2016
Lebein, a Snake Venom Disintegrin, Induces Apoptosis in Human Melanoma Cells
Melanoma, the most threatening form of skin cancer, has a very poor prognosis and is characterized by its very invasive and… Expand
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Review
2016
Review
2016
Effects of Animal Venoms and Toxins on Hallmarks of Cancer
Animal venoms are a cocktail of proteins and peptides, targeting vital physiological processes. Venoms have evolved to assist in… Expand
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2003
2003
Vipera lebetina Venom Contains Two Disintegrins Inhibiting Laminin-binding β1 Integrins*
To explain the myotoxic effects of snake venoms, we searched for inhibitors of α7β1 integrin, the major laminin-binding integrin… Expand
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2001
2001
Amino acid structure and characterization of a heterodimeric disintegrin from Vipera lebetina venom.
A heterodimeric disintegrin designed as lebein was isolated from crude Vipera lebetina venom using gel filtration, anion and… Expand
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