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lactose synthase activity

Known as: UDP-galactose:D-glucose 4-beta-D-galactotransferase activity, UDPgalactose:D-glucose 4-beta-D-galactotransferase activity, UDP-galactose-glucose galactosyltransferase activity 
Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose. [EC:2.4.1.22]
National Institutes of Health

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Lactose Synthase

Papers overview

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Highly Cited
1998
Highly Cited
1998
Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc beta-1,4-galactosyltransferase.
A cDNA encoding a beta-1,4-galactosyltransferase named beta-1,4-GalT II was cloned from a cDNA library of the human breast tumor… 
1985
1985
Possible roles of calcium and calmodulin in mammary gland differentiation in vitro.
In response to insulin, cortisol and prolactin, mammary gland explants from virgin mice will undergo differentiation, as measured… 
1983
1983
Lactogenesis induced by ovariectomy in pregnant rats and its regulation by oestrogen and progesterone.
Highly Cited
1979
Highly Cited
1979
Lobulo-alveolar development of mouse mammary glands is regulated by thyroid hormones.
The mammary glands of euthyroid female C3H/HeN mice undergo a series of morphological changes during development. In glands from… 
1977
1977
Effects of glucocorticoids on casein gene expression in the rabbit.
Milk protein synthesis is initiated by prolactin and a glucocorticoid. In the rabbit, prolactin alone is sufficient. However… 
Highly Cited
1975
Highly Cited
1975
Cross-linking of the components of lactose synthetase with dimethylpimelimidate.
1974
1974
Metabolic adaptations in fatty acid and lactose biosynthesis by sheep mammary tissue during cessation of lactation.
Abstract The effect of involution of fatty acid synthesis, lactose synthesis, and carbon dioxide production by sheep mammary… 
Highly Cited
1973
Highly Cited
1973
Metabolic adaptations during lactogenesis. Fatty acid and lactose synthesis in cow mammary tissue.
1. Mammary-tissue biopsies were obtained from multiparous cows at 30 and 7 days pre partum and 7 and 40 days post partum… 
Highly Cited
1970
Highly Cited
1970
Enzymic assay for galactosyl transferase activity of lactose synthetase and alpha-lactalbumin in purified and crude systems.
1968
1968
The lactose synthetase particles of lactating bovine mammary gland. Preparation of particles with intact lactose synthetase.
1. The particulate form of lactating bovine mammary lactose synthetase activity is shown to be more highly organized than… 
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