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lactic acid secretion

Known as: lactate secretion 
The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue. [GOC:ai]
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Tumor-secreted dickkopf2 accelerates aerobic glycolysis and promotes angiogenesis in colorectal cancer
Angiogenesis is a fundamental process that involves in tumor progression and metastasis. Vascular endothelial growth factor (VEGF… 
Highly Cited
2018
Highly Cited
2018
Double genetic disruption of lactate dehydrogenases A and B is required to ablate the “Warburg effect” restricting tumor growth to oxidative metabolism
Increased glucose consumption distinguishes cancer cells from normal cells and is known as the “Warburg effect” because of… 
Highly Cited
2018
Highly Cited
2018
GLUT1 regulates cell glycolysis and proliferation in prostate cancer
Glucose transporter 1 (GLUT1) plays a critical role in tumorigenesis and tumor progression in multiple cancer types. However, the… 
Highly Cited
2016
Highly Cited
2016
Multi-analyte biosensor interface for real-time monitoring of 3D microtissue spheroids in hanging-drop networks
Microfluidics is becoming a technology of growing interest for building microphysiological systems with integrated read-out… 
Highly Cited
2015
Highly Cited
2015
Infection with Mycobacterium tuberculosis induces the Warburg effect in mouse lungs
To elucidate the little-known bioenergetic pathways of host immune cells in tuberculosis, a granulomatous disease caused by the… 
Review
2013
Review
2013
Cancer-generated lactic acid: a regulatory, immunosuppressive metabolite?
The common preference of cancers for lactic acid‐generating metabolic energy pathways has led to proposals that their… 
Highly Cited
2013
Highly Cited
2013
Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia
Mammalian cells can generate ATP via glycolysis or mitochondrial respiration. Oncogene activation and hypoxia promote glycolysis… 
Highly Cited
2012
Highly Cited
2012
Effect of insulin deprivation on metabolism and metabolism-associated gene transcript levels of in vitro cultured human Sertoli cells.
Highly Cited
1994
Highly Cited
1994
Metabolic Control of Anaerobic Glycolysis (Overexpression of Lactate Dehydrogenase in Transgenic Tomato Roots Supports the Davies-Roberts Hypothesis and Points to a Critical Role for Lactate…
Roots of all plants examined so far have the potential for both ethanol and lactate fermentation. A short burst of lactate… 
Highly Cited
1982
Highly Cited
1982
Regulation of survival of rat pachytene spermatocytes by lactate supply from Sertoli cells.
During incubation of fragments of seminiferous tubules in the absence of glucose, pachytene spermatocytes and round spermatids… 
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