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labradimil

Known as: L-Prolinamide, L-Arginyl-L-prolyl-trans-4- hydroxy-L-prolyl-3-(2- thienyl)-L-alanylglycl -L-seryl-N-(2-((4-((aminoiminomethyl)amino)-1- -carboxybutyl)amino)-1-((4-methoxyphenyl)methyl)ethyl)-, (S-(R*,R*)), Lobradimil 
A synthetic analog of bradykinin. Lobradimil is a potent, specific bradykinin B-2 receptor agonist that stimulates B-2 receptors expressed on the… 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (1)

Cereport
Epithelial CellsReceptor Activation Processcarboplatin/lobradimil

Broader (1)

RMP-7

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
The Bonding Situation in Metalated Ylides
Abstract Quantum chemical calculations have been carried out to study the electronic structure of metalated ylides particularly… 
Review
2014
Review
2014
Review: an exposition of medicinal preponderance of Moringa oleifera (Lank.).
Medicinal plants are believed to be a precious natural reservoir as they are assumed to have paranormal effects for the mankind… 
2013
2013
A new arabinoxylan from green leaves of Litsea glutinosa (Lauraeae): structural and biological studies.
A water soluble new arabinoxylan, isolated through hot water extraction from the green leaves of Litsea glutinosa (Lauraceae) was… 
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Highly Cited
2005
Highly Cited
2005
Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children’s Oncology Group
Backround: Lobradimil is a synthetic bradykinin analog that rapidly and transiently increases the permeability of the blood-brain… 
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Review
2001
Review
2001
The Development of the Bradykinin Agonist Labradimil as a Means to Increase the Permeability of the Blood-Brain Barrier
AbstractLabradimil (Cereport®; also formerly referred to as RMP-7) is a 9-amino-acid peptide designed for selectivity for the… 
2001
2001
Phase I trial of lobradimil (RMP-7) and carboplatin in children with brain tumors
Abstract.Purpose: To determine the maximum tolerated dose (MTD), the incidence and severity of toxicities, and the… 
1989
1989
Unusual tripodal ligands. Synthesis of 2,2-bis(diphenylphosphinomethyl)-1-phenylthiopropane and its group VI complexes
Abstract A hybrid tripodal ligand containing phosphorus and sulfur atoms, 2,2-bis(diphenylphosphinomethyl)-1-phenylthiopropane… 
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Highly Cited
1980
Highly Cited
1980
Suppression of antibody and T cell proliferative responses to L- glutamic acid60-L-alanine30-L-tyrosine10 by a specific monoclonal T cell factor
The synthetic terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) stimulates GAT-specific suppressor T cells in… 
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Highly Cited
1979
Highly Cited
1979
High frequency gyrotrons and their application to tokamak plasma heating
Abstract High frequency (⩾ 200 GHz) gyrotrons are potentially useful for several important applications, including plasma heating… 
1972
1972
Neuropharmacological study of 9 - and 8 -L-tetrahydrocannabinols in monkeys and mice.
Abstract In monkeys, Δ8- and Δ9-THC were both active at 0.5 mg/kg. Animals receiving intravenously 0.5 and 2 mg/kg doses of both… 
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