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labradimil

Known as: L-Prolinamide, L-Arginyl-L-prolyl-trans-4- hydroxy-L-prolyl-3-(2- thienyl)-L-alanylglycl -L-seryl-N-(2-((4-((aminoiminomethyl)amino)-1- -carboxybutyl)amino)-1-((4-methoxyphenyl)methyl)ethyl)-, (S-(R*,R*)), Lobradimil 
A synthetic analog of bradykinin. Lobradimil is a potent, specific bradykinin B-2 receptor agonist that stimulates B-2 receptors expressed on the… Expand
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (1)

Cereport
Epithelial CellsReceptor Activation Processcarboplatin/lobradimil

Broader (1)

RMP-7

Papers overview

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2017
2017
The Bonding Situation in Metalated Ylides
Abstract Quantum chemical calculations have been carried out to study the electronic structure of metalated ylides particularly… Expand
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2013
2013
A new arabinoxylan from green leaves of Litsea glutinosa (Lauraeae): structural and biological studies.
A water soluble new arabinoxylan, isolated through hot water extraction from the green leaves of Litsea glutinosa (Lauraceae) was… Expand
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Highly Cited
2005
Highly Cited
2005
Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children’s Oncology Group
Backround: Lobradimil is a synthetic bradykinin analog that rapidly and transiently increases the permeability of the blood-brain… Expand
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2004
2004
Pharmacokinetics of carboplatin administered with lobradimil to pediatric patients with brain tumors
AbstractPurposeTo determine the pharmacokinetics of adaptively dosed carboplatin when administered in combination with the… Expand
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Review
2001
Review
2001
The Development of the Bradykinin Agonist Labradimil as a Means to Increase the Permeability of the Blood-Brain Barrier
AbstractLabradimil (Cereport®; also formerly referred to as RMP-7) is a 9-amino-acid peptide designed for selectivity for the… Expand
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2001
2001
Phase I trial of lobradimil (RMP-7) and carboplatin in children with brain tumors
Abstract.Purpose: To determine the maximum tolerated dose (MTD), the incidence and severity of toxicities, and the… Expand
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1989
1989
Unusual tripodal ligands. Synthesis of 2,2-bis(diphenylphosphinomethyl)-1-phenylthiopropane and its group VI complexes
Abstract A hybrid tripodal ligand containing phosphorus and sulfur atoms, 2,2-bis(diphenylphosphinomethyl)-1-phenylthiopropane… Expand
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Highly Cited
1980
Highly Cited
1980
Suppression of antibody and T cell proliferative responses to L- glutamic acid60-L-alanine30-L-tyrosine10 by a specific monoclonal T cell factor
The synthetic terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) stimulates GAT-specific suppressor T cells in… Expand
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Highly Cited
1979
Highly Cited
1979
High frequency gyrotrons and their application to tokamak plasma heating
Abstract High frequency (⩾ 200 GHz) gyrotrons are potentially useful for several important applications, including plasma heating… Expand
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1972
1972
Neuropharmacological study of 9 - and 8 -L-tetrahydrocannabinols in monkeys and mice.
Abstract In monkeys, Δ8- and Δ9-THC were both active at 0.5 mg/kg. Animals receiving intravenously 0.5 and 2 mg/kg doses of both… Expand
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