labradimil

Known as: L-Prolinamide, L-Arginyl-L-prolyl-trans-4- hydroxy-L-prolyl-3-(2- thienyl)-L-alanylglycl -L-seryl-N-(2-((4-((aminoiminomethyl)amino)-1- -carboxybutyl)amino)-1-((4-methoxyphenyl)methyl)ethyl)-, (S-(R*,R*)), Lobradimil 
A synthetic analog of bradykinin. Lobradimil is a potent, specific bradykinin B-2 receptor agonist that stimulates B-2 receptors expressed on the… (More)
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (1)

Cereport
Epithelial CellsReceptor Activation Processcarboplatin/lobradimil

Broader (1)

RMP-7

Papers overview

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2013
2013
A new arabinoxylan from green leaves of Litsea glutinosa (Lauraeae): structural and biological studies.
A water soluble new arabinoxylan, isolated through hot water extraction from the green leaves of Litsea glutinosa (Lauraceae) was… (More)
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2006
2006
Portal Verification Using the KODAK ACR 2000 RT Storage Phosphor Plate System and EC® Films
The suitability of the storage phosphor plate system ACR 2000 RT (Eastman Kodak Corp., Rochester, MN, USA), that is destined for… (More)
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2005
2005
Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children’s Oncology Group
Backround: Lobradimil is a synthetic bradykinin analog that rapidly and transiently increases the permeability of the blood-brain… (More)
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2002
2002
Two new steroidal saponins from Tacca plantaginea
Two new C27 steroidal glycosides, named taccaoside A (1) and B (2), were isolated from the traditional Chinese herb Tacca… (More)
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Review
2001
Review
2001
The development of the bradykinin agonist labradimil as a means to increase the permeability of the blood-brain barrier: from concept to clinical evaluation.
Labradimil (Cereport; also formerly referred to as RMP-7) is a 9-amino-acid peptide designed for selectivity for the bradykinin… (More)
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2001
2001
Phase I trial of lobradimil (RMP-7) and carboplatin in children with brain tumors
Purpose: To determine the maximum tolerated dose (MTD), the incidence and severity of toxicities, and the pharmacokinetics of… (More)
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2001
2001
Bradykinin modulation of tumor vasculature: II. activation of nitric oxide and phospholipase A2/prostaglandin signaling pathways synergistically modifies vascular physiology and morphology to enhance…
Intravenous infusions of the bradykinin agonist Cereport (labradimil, formerly RMP-7) enhance delivery of concomitantly… (More)
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2001
2001
Bradykinin modulation of tumor vasculature: I. Activation of B2 receptors increases delivery of chemotherapeutic agents into solid peripheral tumors, enhancing their efficacy.
Delivery of chemotherapeutic agents to solid peripheral tumors is compromised because the impaired microvasculature within and… (More)
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1980
1980
Suppression of antibody and T cell proliferative responses to L- glutamic acid60-L-alanine30-L-tyrosine10 by a specific monoclonal T cell factor
The synthetic terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) stimulates GAT-specific suppressor T cells in… (More)
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1979
1979
High frequency gyrotrons and their application to tokamak plasma heating
  • Richard J. Temkin, K. Kreischer, S. M. Wolfe, Daniel R. Cohn, Benjamin Lax
  • 1979
High frequency (> 200 GHz) gyrotrons are potentially useful for several important applications, including plasma heating and… (More)
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