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kinetochore binding

Interacting selectively and non-covalently with a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which… 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Dynamics of CENP-N kinetochore binding during the cell cycle
Accurate chromosome segregation requires the assembly of kinetochores, multiprotein complexes that assemble on the centromere of… 
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Highly Cited
2009
Highly Cited
2009
Roles for the Conserved Spc105p/Kre28p Complex in Kinetochore-Microtubule Binding and the Spindle Assembly Checkpoint
Background Kinetochores attach sister chromatids to microtubules of the mitotic spindle and orchestrate chromosome disjunction at… 
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2009
2009
Identification of FANCA as a protein interacting with centromere-associated protein E.
This study sought to isolate and identify proteins that interact with centromere-associated protein E (CENPE), provide new clues… 
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Highly Cited
2007
Highly Cited
2007
Shugoshin 1 Plays a Central Role in Kinetochore Assembly and is Required for Kinetochore Targeting of Plk1
Physical connection between the sister chromatids is mediated by the cohesin protein complex. During prophase, cohesin is removed… 
Highly Cited
2003
Highly Cited
2003
Human CLASP1 Is an Outer Kinetochore Component that Regulates Spindle Microtubule Dynamics
One of the most intriguing aspects of mitosis is the ability of kinetochores to hold onto plus ends of microtubules that are… 
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Highly Cited
2002
Highly Cited
2002
BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1
The spindle checkpoint delays anaphase onset until all chromosomes have attached properly to the mitotic spindle. Checkpoint… 
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Highly Cited
2002
Highly Cited
2002
Kinetochore localisation of the DNA damage response component 53BP1 during mitosis.
53BP1 is a vertebrate BRCT motif protein, originally described as a direct interactor of p53, which has recently been shown to be… 
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2002
2002
BubR 1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad 1
he spindle checkpoint delays anaphase onset until all chromosomes have attached properly to the mitotic spindle. Checkpoint… 
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Highly Cited
2001
Highly Cited
2001
Spindle Checkpoint Protein Bub1 Is Required for Kinetochore Localization of Mad1, Mad2, Bub3, and Cenp-E, Independently of Its Kinase Activity
The spindle checkpoint inhibits the metaphase to anaphase transition until all the chromosomes are properly attached to the… 
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Highly Cited
1998
Highly Cited
1998
Characterization of the Kinetochore Binding Domain of CENP-E Reveals Interactions with the Kinetochore Proteins CENP-F and hBUBR1
We have identified a 350–amino acid domain in the kinetochore motor CENP-E that specifies kinetochore binding in mitosis but not… 
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