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ketol-acid reductoisomerase activity
Known as:
(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)
, 2-hydroxy-3-keto acid reductoisomerase activity
, dihydroxyisovalerate dehydrogenase (isomerizing) activity
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Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+. [EC:1.1.1.86]
National Institutes of Health
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Papers overview
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2019
2019
Metabolic and transcriptional analyses in response to potent inhibitors establish MEP pathway as major route for camptothecin biosynthesis in Nothapodytes nimmoniana (Graham) Mabb
G. A. Rather
,
Arti Sharma
,
S. Jeelani
,
P. Misra
,
Veenu Kaul
,
S. K. Lattoo
BMC Plant Biology
2019
Corpus ID: 195873555
Nothapodytes nimmoniana, a plant of pivotal medicinal significance is a source of potent anticancer monoterpene indole alkaloid…
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2018
2018
Steroid Degradation in Comamonas testosteroni TA441: Identification of Metabolites and the Genes Involved in the Reactions Necessary before D-Ring Cleavage
Masae Horinouchi
,
H. Koshino
,
M. Maloň
,
H. Hirota
,
Toshiaki Hayashi
Applied and Environmental Microbiology
2018
Corpus ID: 52174632
Studies on representative steroid degradation bacteria Rhodococcus equi (Nocardia restrictus) and Comamonas testosteroni were…
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2015
2015
Flavonoids: true or promiscuous inhibitors of enzyme? The case of deoxyxylulose phosphate reductoisomerase.
D. Tritsch
,
Catherine Zinglé
,
M. Rohmer
,
C. Grosdemange-Billiard
Bioorganic chemistry (Print)
2015
Corpus ID: 30636535
2013
2013
Isomerizing ethenolysis as an efficient strategy for styrene synthesis.
Sabrina Baader
,
D. Ohlmann
,
L. Goossen
Chemistry
2013
Corpus ID: 883563
A shrinking chain: A bimetallic system consisting of [{Pd(μ-Br)(tBu3P)}2] and a ruthenium metathesis catalyst has been found to…
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Highly Cited
2012
Highly Cited
2012
Isomerizing olefin metathesis as a strategy to access defined distributions of unsaturated compounds from fatty acids.
D. Ohlmann
,
Nicole Tschauder
,
J. Stockis
,
K. Goossen
,
M. Dierker
,
L. Goossen
Journal of the American Chemical Society
2012
Corpus ID: 25524193
The dimeric palladium(I) complex [Pd(μ-Br)(t)Bu(3)P](2) was found to possess unique activity for the catalytic double-bond…
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2004
2004
Inhibition of isoprene biosynthesis pathway enzymes by phosphonates, bisphosphonates, and diphosphates.
Feng Cheng
,
E. Oldfield
Journal of Medicinal Chemistry
2004
Corpus ID: 24989241
We have investigated the docking of a variety of inhibitors and substrates to the isoprene biosynthesis pathway enzymes farnesyl…
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2000
2000
Plasmodium falciparum: detection of the deoxyxylulose 5-phosphate reductoisomerase activity.
J. Wiesner
,
M. Hintz
,
+4 authors
H. Jomaa
Experimental parasitology
2000
Corpus ID: 41639824
Abstract Wiesner, J., Hintz, M., Altincicek, B., Sanderbrand, S., Weidemeyer, C., Beck, E., and Jomaa, H. 2000. Plasmodium…
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1992
1992
Isolation and kinetic properties of acetohydroxy acid isomeroreductase from spinach (Spinacia oleracea) chloroplasts overexpressed in Escherichia coli.
R. Dumas
,
D. Job
,
J. Ortholand
,
G. Emeric
,
A. Greiner
,
R. Douce
Biochemical Journal
1992
Corpus ID: 26319974
Acetohydroxy acid isomeroreductase catalyses a two-step reaction, an alkyl migration and a NADPH-dependent reduction, in the…
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1991
1991
The product of the Rhizobium meliloti ilvC gene is required for isoleucine and valine synthesis and nodulation of alfalfa
O. M. Aguilar
,
D. Grasso
Journal of Bacteriology
1991
Corpus ID: 32805353
Tn5-induced mutants of Rhizobium meliloti that require the amino acids isoleucine and valine for growth on minimal medium were…
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1973
1973
Isoleucine and Valine Metabolism in Escherichia coli XXII. A Pleiotropic Mutation Affecting Induction of Isomeroreductase Activity
W. Pledger
,
H. E. Umbarger
Journal of Bacteriology
1973
Corpus ID: 12134003
The ilvC gene product, acetohydroxy acid isomeroreductase, an enzyme essential for isoleucine and valine formation, is subject to…
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