isothiazole

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1964-2018
024619642018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
A series of emissive ribonucleoside purine mimics, all comprised of an isothiazolo[4,3-d]pyrimidine core, was prepared using a… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
Is this relevant?
2012
2012
MEK-1 and MEK-2 are dual-specificity kinases and important components in the mitogen-activated protein kinase pathway. These… (More)
Is this relevant?
2010
2010
In this study, quantitative structure-activity/property models are developed for modeling and predicting both MEK inhibitory… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Is this relevant?
2007
2007
We recently described the synthesis and antiviral activity of the compounds 5-phenyl-3-(4-cyano-5-phenylisothiazol-3-yl… (More)
Is this relevant?
2007
2007
Isothiazole analogs were discovered as a novel class of active-site inhibitors of HCV NS5B polymerase. The best compound has an… (More)
Is this relevant?
2006
2006
Regioselective palladium catalysed coupling reactions are achieved in good to high yields, starting from either 3,5-dichloro- or… (More)
Is this relevant?
2006
2006
The design, synthesis, and biological evaluation of potent inhibitors of the TrkA kinase is presented. A homology model is… (More)
Is this relevant?
2006
2006
The synthesis and biological investigation of the series of amide and ester derivatives 10-20 of 5-(4-chlorobenzoyl)amino-3… (More)
Is this relevant?
2003
2003
Signaling through vascular endothelial growth factor (VEGF) receptors (VEGFRs) is a key pathway initiating endothelial cell… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
1992
1992
The in vitro effects of four isothiazoles [5,5'-diphenyl-3,3'-diisothiazole disulfide, 5-phenyl-3-mercapto-isothiazole, 5,5'-(4… (More)
Is this relevant?