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isomazole

 
National Institutes of Health

Papers overview

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1994
1994
1 The effect of sulmazole and several structurally related analogues on cardiac sarcoplasmic reticulum (SR) Ca2+‐release channel… Expand
1993
1993
The synthesis and phosphodiesterase (PDE) inhibitory profile of a series of imidazopyridines, including sulmazole and isomazole… Expand
1991
1991
The phosphodiesterase (PDE) inhibitor isomazole increased the force of contraction to 278.3 ± 89.1% (n = 7) of the predrug value… Expand
1990
1990
A series of "A" ring substituted sulmazole and isomazole analogues have been prepared and evaluated as inotropic agents. pKA's… Expand
1989
1989
Isomazole matrix tablet formulations, with various concentrations of hydroxypropyl methylcellulose (HPMC) hydrogel, were prepared… Expand
1989
1989
Myocardial contractile force may be altered not only by changing intracellular free Ca2+ but also by increasing or decreasing the… Expand
1989
1989
Acute, subchronic, and chronic toxicity studies were conducted in dogs with the new vasodilator/cardiotonic drug isomazole (IMZ… Expand
1988
1988
We report here that the new cardiotonic agent isomazole increases the Ca2+ responsiveness of skinned myocardial fibres from… Expand
Highly Cited
1987
Highly Cited
1987
Several novel cardiotonic vasodilators including bipyridines (amrinone and milrinone), imidazolones (enoximone and piroximone… Expand
1986
1986
The contractile state of cat papillary muscles was increased by isomazole in a concentration-dependent manner; inotropic effects… Expand