isomazole
National Institutes of Health
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1 The effect of sulmazole and several structurally related analogues on cardiac sarcoplasmic reticulum (SR) Ca2+‐release channel…
The synthesis and phosphodiesterase (PDE) inhibitory profile of a series of imidazopyridines, including sulmazole and isomazole…
The phosphodiesterase (PDE) inhibitor isomazole increased the force of contraction to 278.3 ± 89.1% (n = 7) of the predrug value…
A series of "A" ring substituted sulmazole and isomazole analogues have been prepared and evaluated as inotropic agents. pKA's…
Isomazole analogues which have achiral electron withdrawing substituents at the 4′‐position and analogues with heterocyclic ‘C…
Isomazole matrix tablet formulations, with various concentrations of hydroxypropyl methylcellulose (HPMC) hydrogel, were prepared…
Myocardial contractile force may be altered not only by changing intracellular free Ca2+ but also by increasing or decreasing the…
Several novel cardiotonic vasodilators including bipyridines (amrinone and milrinone), imidazolones (enoximone and piroximone…
The contractile state of cat papillary muscles was increased by isomazole in a concentration-dependent manner; inotropic effects…