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isomalathion
Known as:
((methoxy(methylthio)phosphinyl)thio)butanedioic acid diethyl ester
, S-(1,2-dicarbethoxyethyl)-O,S-dimethyl phosphorodithioate
National Institutes of Health
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Malathion
Papers overview
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2003
2003
Stereoselective inactivation of Torpedo californica acetylcholinesterase by isomalathion: inhibitory reactions with (1R)- and (1S)-isomers proceed by different mechanisms.
J. Doorn
,
C. Thompson
,
R. Christner
,
R. Richardson
Chemical Research in Toxicology
2003
Corpus ID: 38293650
The present study was undertaken to test the hypothesis that acetylcholinesterase (AChE) inhibition by isomalathion stereoisomers…
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2000
2000
Inhibition of acetylcholinesterase by (1S,3S)-isomalathion proceeds with loss of thiomethyl: kinetic and mass spectral evidence for an unexpected primary leaving group.
J. Doorn
,
D. Gage
,
M. Schall
,
T. Talley
,
C. Thompson
,
R. Richardson
Chemical Research in Toxicology
2000
Corpus ID: 7333345
Previous work demonstrated kinetically that inhibition of mammalian acetylcholinesterase (AChE) by (1S)-isomalathions may proceed…
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1999
1999
Kinetic evidence for different mechanisms of acetylcholinesterase inhibition by (1R)- and (1S)-stereoisomers of isomalathion.
S. Jianmongkol
,
B. Marable
,
C. Berkman
,
T. Talley
,
C. Thompson
,
R. Richardson
Toxicology and Applied Pharmacology
1999
Corpus ID: 41944209
Inhibition of acetylcholinesterase (AChE) by isomalathion has been assumed to proceed by expulsion of diethyl thiosuccinyl to…
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1997
1997
Effects of malathion metabolites on degranulation of and mediator release by human and rat basophilic cells.
S. Xiong
,
K. Rodgers
Journal of Toxicology and Environmental Health…
1997
Corpus ID: 27324606
In the present study, the effects of malathion and malathion derivatives on histamine and beta-hexosaminidase release by RBL-1…
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1996
1996
Relative potencies of the four stereoisomers of isomalathion for inhibition of hen brain acetylcholinesterase and neurotoxic esterase in vitro.
S. Jianmongkol
,
C. Berkman
,
C. Thompson
,
R. Richardson
Toxicology and Applied Pharmacology
1996
Corpus ID: 9057634
The cholinergic toxicity of malathion is exacerbated by its isomerization product, isomalathion, which inhibits detoxifying…
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1993
1993
Synthesis, absolute configuration, and analysis of malathion, malaoxon, and isomalathion enantiomers.
C. Berkman
,
C. Thompson
,
S. Perrin
Chemical Research in Toxicology
1993
Corpus ID: 21625550
Syntheses of the enantiomers of malathion, malaoxon, and isomalathion are reported herein. Malathion enantiomers were prepared…
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1993
1993
Interaction of acetylcholinesterase with the enantiomers of malaoxon and isomalathion.
C. Berkman
,
D. Quinn
,
C. Thompson
Chemical Research in Toxicology
1993
Corpus ID: 39608200
The biomolecular reaction constants (ki), dissociation constants (Kd), and phosphorylation constants (kp) were determined for the…
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1993
1993
Kinetics of the postinhibitory reactions of acetylcholinesterase poisoned by chiral isomalathion: a surprising nonreactivation induced by the RP stereoisomers.
C. Berkman
,
S. Ryu
,
D. Quinn
,
C. Thompson
Chemical Research in Toxicology
1993
Corpus ID: 44437753
Inhibitory (ki), spontaneous (k0), and oxime-mediated reactivation (k(oxime)) reaction kinetics for the four stereoisomers of…
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1982
1982
Toxicity and metabolism of malathion and its impurities in isolated rat hepatocytes: role of glutathione.
J. Malik
,
K. Summer
Toxicology and Applied Pharmacology
1982
Corpus ID: 37319296
Highly Cited
1981
Highly Cited
1981
Interaction of some trialkyl phosphorothiolates with acetylcholinesterase. Characterization of inhibition, aging and reactivation.
B. Clothier
,
M. Johnson
,
E. Reiner
Biochimica et Biophysica Acta
1981
Corpus ID: 46482598
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