isoguanine

Known as: crotonoside, 2-OH-Ade, 2-hydroxyadenine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1948-2017
051019482016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
The blockage of transcription elongation by RNA polymerase II (RNAPII) at DNA lesions on the transcribed strand is a serious… (More)
Is this relevant?
2007
2007
2-Hydroxyadenine (2-OH-A), a product of DNA oxidation, is a potential source of mutations. We investigated how representative DNA… (More)
Is this relevant?
2006
2006
The MYH (MutY glycosylase homologue) increases replication fidelity by removing adenines or 2-hydroxyadenine misincorporated… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
2005
2005
E. coli MutY excises adenine from duplex DNA when it is mispaired with the mutagenic oxidative lesion 7,8-dihydro-8-oxo-2… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Two candidate human orthologs of Escherichia coli MutM/Nei were recently identified in the human genome database, and one of… (More)
Is this relevant?
2001
2001
The human MTH1 gene located on chromosome 7p22 consists of 5 major exons. MTH1 gene produces seven types of mRNAs and the B-type… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
An enzyme activity introducing an alkali-labile site at 2-hydroxyadenine (2-OH-A) in double-stranded oligonucleotides was… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
1995
1995
We found that hydroxylation occurs at the C-2 position of adenine by oxygen radical treatment (Fe2+-EDTA) of dA, dATP, and single… (More)
Is this relevant?
1994
1994
Ferric nitrilotriacetate (Fe-NTA) causes renal proximal tubular necrosis, a consequence of iron ion-mediated free-radical… (More)
Is this relevant?
1992
1992
Free radical-induced damage to DNA in vivo is implicated to play a role in carcinogenesis. Evidence exists that DNA damage by… (More)
Is this relevant?