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iron-responsive element binding

Known as: IRE binding 
Interacting selectively and non-covalently with the iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of… 
National Institutes of Health

Papers overview

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2020
2020
Genetic Analysis of EGLN1 C127S Variant in Taiwanese Parkinson's Disease
Parkinson's disease (PD) is a neurodegenerative disorder related to nigrostriatal dopaminergic neuron degeneration and iron… 
2017
2017
MicroRNA-related genetic variants in iron regulatory genes, dietary iron intake, microRNAs and lung cancer risk
Background Genetic variations in MicroRNA (miRNA) binding sites may alter structural accessibility of miRNA binding sites to… 
2000
2000
In vivo, high-resolution analysis of yeast and mammalian RNA-protein interactions, RNA structure, RNA splicing and ribozyme cleavage by use of terminal transferase-dependent PCR.
We have investigated the analysis of RNA by use of terminal transferase-dependent PCR (TDPCR), a procedure previously used for… 
Highly Cited
1996
Highly Cited
1996
Phosphorylation and Activation of both Iron Regulatory Proteins 1 and 2 in HL-60 Cells (*)
Iron regulatory proteins (IRPs) are RNA-binding proteins that post-transcriptionally regulate synthesis of iron uptake… 
1996
1996
The Locus-specific Enhancer Activity of the Class I Major Histocompatibility Complex Interferon-responsive Element Is Associated with a γ-Interferon (IFN)-inducible Factor Distinct from STAT1α, p48…
Recent analyses of the upstream regulatory regions of the class I major histocompatibility complex genes in higher primates… 
Highly Cited
1993
Highly Cited
1993
The interaction between the iron-responsive element binding protein and its cognate RNA is highly dependent upon both RNA sequence and structure.
To assess the influence of RNA sequence/structure on the interaction RNAs with the iron-responsive element binding protein (IRE… 
Highly Cited
1992
Highly Cited
1992
Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding.
The translation of ferritin mRNA and degradation of transferrin receptor mRNA are regulated by the interaction of an RNA-binding… 
Highly Cited
1992
Highly Cited
1992
Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: role of the iron-sulfur cluster.
Several mechanisms of posttranscriptional gene regulation are involved in regulation of the expression of essential proteins of… 
Highly Cited
1992
Highly Cited
1992
Iron regulates the activity of the iron-responsive element binding protein without changing its rate of synthesis or degradation.
Highly Cited
1990
Highly Cited
1990
Structural requirements of iron-responsive elements for binding of the protein involved in both transferrin receptor and ferritin mRNA post-transcriptional regulation.
The synthesis of both transferrin receptor (TfR) and ferritin is regulated post-transcriptionally by iron. This is mediated by… 
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