ipomoeassin B

Ipomoeassin F is a potent natural cytotoxin that inhibits growth of many tumor cell lines with single-digit nanomolar potency… (More)

Natural product synthesis has many applications in the field of chemical biology, due to the protein binding affinity to the… (More)

Ipomoeassin F, a plant-derived macrolide, exhibited single-digit nanomolar growth inhibition activity against many cancer cell… (More)

An efficient synthetic route for ipomoeassin F and its tiglate-modified analogues was developed. The route features late-stage… (More)

Ipomoeassin F, a macrolide glycoresin containing an embedded disaccharide, possesses potent in vitro antitumor activity with an… (More)

A concise, flexible, and efficient total synthesis of the cytotoxic resin glycosides ipomoeassin B (1) and ipomoeassin E (2) is… (More)