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ipomoeassin B

National Institutes of Health

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1 relation

Broader (1)

Glycoconjugates

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Coibamide A Targets Sec61 to Prevent Biogenesis of Secretory and Membrane Proteins
Coibamide A (CbA) is a marine natural product with potent antiproliferative activity against human cancer cells and a unique… 
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2019
2019
Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation
Ipomoeassin F is a potent natural cytotoxin that inhibits growth of many tumor cell lines with single-digit nanomolar potency… 
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2018
2018
Chemical Strategies for Drug Development of Fucose-Truncated Ipomoeassin F Analogues
Natural product synthesis has many applications in the field of chemical biology, due to the protein binding affinity to the… 
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2018
2018
New insights into structure-activity relationship of ipomoeassin F from its bioisosteric 5-oxa/aza analogues.
Ipomoeassin F, a plant-derived macrolide, exhibited single-digit nanomolar growth inhibition activity against many cancer cell… 
2017
2017
Synergistic Contribution of Tiglate and Cinnamate to Cytotoxicity of Ipomoeassin F.
An efficient synthetic route for ipomoeassin F and its tiglate-modified analogues was developed. The route features late-stage… 
2015
2015
Total Synthesis and Biological Evaluation of Ipomoeassin F and Its Unnatural 11R-Epimer.
Ipomoeassin F, a macrolide glycoresin containing an embedded disaccharide, possesses potent in vitro antitumor activity with an… 
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Highly Cited
2007
Highly Cited
2007
Total syntheses of ipomoeassin B and E.
A concise, flexible, and efficient total synthesis of the cytotoxic resin glycosides ipomoeassin B (1) and ipomoeassin E (2) is… 
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