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iodoazomycin arabinoside

Known as: 1-(5-iodo-5-deoxy-beta-arabinofuranosyl)-2-nitroimidazole, IAZA 
National Institutes of Health

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Nitroimidazoles

Papers overview

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2010
2010
Simple, column purification technique for the fully automated radiosynthesis of [18F]fluoroazomycinarabinoside ([18F]FAZA).
2003
2003
Mercury selective electrochemical sensor based on a double armed crown ether as ionophore
PVC based membranes of a double armed crown ether, N, N'-dibenzyl, 1,4,10,13-tetraoxa-7, 16-diaza cyclooctadecane (I) as… 
2003
2003
Synthesis of 1-β- D -(5-Deoxy-5-iodoarabinofuranosyl)-2-nitroimidazole (β-IAZA): A Novel Marker of Tissue Hypoxia
The present work describes the synthesis of the b-isomer of 1-a-D-(5-deoxy-5-iodoarabinofuranosyl)-2-nitroimidazole (IAZA… 
2001
2001
Dosimetry estimations for 123I-IAZA in healthy volunteers.
UNLABELLED 123I-Labeled iodoazomycin arabinoside (IAZA) is a marker of hypoxia in vivo. It has been used clinically to image… 
1999
1999
Effects of methoxyflurane anesthesia on the pharmacokinetics of 125I-IAZA in Sprague-Dawley rats.
1999
1999
Clinical pharmacokinetics of 123I-IAZA in healthy volunteers.
123I-labelled iodoazomycin arabinoside (123I-IAZA) is an experimental radiopharmaceutical that has been shown to have clinical… 
1998
1998
A rapid and simple assay to determine the blood and urine concentrations of 1-(5-[123/125I]iodo-5-deoxyarabinofuranosyl)-2-nitroimidazole, a hypoxic cell marker.
Highly Cited
1996
Highly Cited
1996
Measurement of hypoxia in human tumours by non-invasive spect imaging of iodoazomycin arabinoside.
Tumour oxygenation status in individual patients may be assessed using the bioreduction and linkage of 2-nitroimidazole markers… 
1996
1996
Prediction of tumour hypoxia and radioresistance with nuclear medicine markers.
Second-generation nuclear medicine markers of tumour hypoxia have been synthesised and screened for hypoxic marking activity in… 
Highly Cited
1991
Highly Cited
1991
Radioiodinated 1-(5-iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (iodoazomycin arabinoside: IAZA): a novel marker of tissue hypoxia.
1-(5-Iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (IAZA) has been synthesised and labeled with 125I. Radioiodinated… 
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