Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Known as: apoptosis in response to ER stress, endoplasmic reticulum stress-induced apoptosis, intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress 
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Endoplasmic reticulum (ER) stress has been implicated in the pathology of cerebral ischemia. During prolonged period of stress or… Expand
Is this relevant?
2010
2010
A better understanding of apoptotic signaling in B-chronic lymphocytic leukemia (B-CLL) cells may help to define new therapeutic… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2010
2010
The potential pro-survival role of phosphatidylinositol 3-kinase (PI3K)/Akt during endoplasmic reticulum stress has been well… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
The E693Delta mutation within the amyloid precursor protein (APP) has been suggested to cause dementia via the enhanced formation… Expand
Is this relevant?
2008
2008
PON2 (paraoxonase-2) is a ubiquitously expressed antioxidative protein which is largely found in the ER (endoplasmic reticulum… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Primary open-angle glaucoma with elevated intraocular pressure is a leading cause of blindness worldwide. Mutations of myocilin… Expand
Is this relevant?
Review
2007
Review
2007
Endopalsmic reticulum (ER) is specialized organelle to maintain the integrity of secreted and membranous proteins. ER also senses… Expand
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Dysregulation of apoptosis is involved in a wide spectrum of disease ranging from proliferative to degenerative disorders. An… Expand
Is this relevant?
Review
2005
Review
2005
Apoptosis or programmed cell death is a process with typical morphological characteristics including plasma membrane blebbing… Expand
  • table 1
  • figure 1
  • table 2
Is this relevant?