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intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Known as: apoptosis in response to ER stress, endoplasmic reticulum stress-induced apoptosis, intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress 
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
A better understanding of apoptotic signaling in B-chronic lymphocytic leukemia (B-CLL) cells may help to define new therapeutic… 
Highly Cited
2009
Highly Cited
2009
The E693Delta mutation within the amyloid precursor protein (APP) has been suggested to cause dementia via the enhanced formation… 
Highly Cited
2008
Highly Cited
2008
PON2 (paraoxonase-2) is a ubiquitously expressed antioxidative protein which is largely found in the ER (endoplasmic reticulum… 
Highly Cited
2007
Highly Cited
2007
Primary open-angle glaucoma with elevated intraocular pressure is a leading cause of blindness worldwide. Mutations of myocilin… 
Review
2006
Review
2006
The efficient functioning of the endoplasmic reticulum (ER) is essential for most cellular activities and survival. Conditions… 
Highly Cited
2006
Highly Cited
2006
It has been proposed that in autosomal recessive juvenile parkinsonism (AR‐JP), a ubiquitin ligase (E3) Parkin, which is involved… 
Review
2005
Review
2005
Apoptosis or programmed cell death is a process with typical morphological characteristics including plasma membrane blebbing… 
Review
2002
Review
2002
Apoptosis, a molecularly regulated form of cell death, is essential for the normal functioning and homeostasis of most…