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interferon-gamma biosynthetic process

Known as: interferon type II biosynthesis, interferon-gamma anabolism, interferon-gamma formation 
The chemical reactions and pathways resulting in the formation of interferon-gamma. Interferon gamma is the only member of the type II interferon… Expand
National Institutes of Health

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interferon-gamma production

Papers overview

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Highly Cited
2004
Highly Cited
2004
Prostaglandin E2 is a potent regulator of interleukin-12- and interleukin-18-induced natural killer cell interferon-gamma synthesis.
Synthesis of interferon (IFN)-gamma by natural killer (NK) cells is an important pro-inflammatory event with interleukin (IL)-12… Expand
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Highly Cited
2004
Highly Cited
2004
Hepatitis C virus core selectively suppresses interleukin-12 synthesis in human macrophages by interfering with AP-1 activation.
Hepatitis C virus (HCV) is remarkably efficient at establishing persistent infection, suggesting that it has evolved one or more… Expand
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2002
2002
Adenosine acts through an A3 receptor to prevent the induction of murine anti-CD3-activated killer T cells.
Adenosine, a purine nucleoside found at high levels in solid tumors, is able to suppress the recognition/adhesion and effector… Expand
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2000
2000
Modulation of human monocyte activities by tranilast, SB 252218, a compound demonstrating efficacy in restenosis.
Tranilast (SB 252218) is a compound initially identified as an anti-atopic agent. Recently the compound has demonstrated clear… Expand
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1997
1997
Functional analysis of monocyte subsets in surgical sepsis.
BACKGROUND Sepsis still remains a major cause of death after surgery. Impaired monocyte (Mphi) function and disruption of… Expand
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Highly Cited
1997
Highly Cited
1997
Influence of fatty acid ethanolamides and delta9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells.
The effects of arachidonic acid ethanolamide (anandamide), palmitoylethanolamide and delta9-tetrahydrocannabinol on the… Expand
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1996
1996
Anti-inflammatory effects of theophylline: modulation of cytokine production.
BACKGROUND The basis for the efficacy of theophylline in the treatment of asthma remains enigmatic. Although commonly classified… Expand
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1994
1994
In vivo effects of glucocorticoids on IgE production.
Recent in vitro investigations have demonstrated that corticosteroids in combination with interleukin-4 induce the synthesis of… Expand
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Highly Cited
1993
Highly Cited
1993
Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses.
The discovery of new cytokines normally relies on a prior knowledge of at least one of their biological effects, which is used as… Expand
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1991
1991
Acquired immunity of A/J mice to mouse hepatitis virus 3 infection: dependence on interferon-gamma synthesis and macrophage sensitivity to interferon-gamma.
Coronavirus-free A/J mice (A/J-), in contrast to those naturally infected with coronavirus (A/J+), were shown to be susceptible… Expand
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