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integrin-mediated signaling pathway

Known as: integrin-mediated signalling pathway 
A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Mycobacterium tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of β2 integrin-mediated signalling pathway.
Establishment of infection by facultative intracellular pathogen Mycobacterium tuberculosis (Mtb) requires adherence to and… Expand
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2017
2017
M. tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of β2 integrin-mediated signaling pathway: Mycobacterium tuberculosis Mce3C binds to β2 integrin
 
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2016
2016
Lunasin suppresses the migration and invasion of breast cancer cells by inhibiting matrix metalloproteinase-2/-9 via the FAK/Akt/ERK and NF-κB signaling pathways.
Lunasin is a naturally existing bioactive peptide with an Arg-Gly-Asp (RGD) motif, which competes with integrins to bind with the… Expand
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2015
2015
The role of Cas-L/NEDD9 as a regulator of collagen-induced arthritis in a murine model.
Cas-L/NEDD9 is a cytoplasmic docking protein downstream of β1 integrin-mediated signaling pathway and is essential for cellular… Expand
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2014
2014
The Focal Adhesion-Localized CdGAP Regulates Matrix Rigidity Sensing and Durotaxis
Motile cells are capable of sensing the stiffness of the surrounding extracellular matrix through integrin-mediated focal… Expand
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2011
2011
Mechanical stimuli and IL-13 interact at integrin adhesion complexes to regulate expression of smooth muscle myosin heavy chain in airway smooth muscle tissue.
Airway smooth muscle phenotype may be modulated in response to external stimuli under physiological and pathophysiological… Expand
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Highly Cited
2010
Highly Cited
2010
Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3.
One emerging model for the development of drug-resistant tumors utilizes a pool of self-renewing malignant progenitors known as… Expand
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2010
2010
Calcium regulates cyclic compression-induced early changes in chondrocytes during in vitro cartilage tissue formation.
A single application of cyclic compression (1kPa, 1Hz, 30min) to bioengineered cartilage results in improved tissue formation… Expand
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2004
2004
Translocation of caveolin regulates stretch-induced ERK activity in vascular smooth muscle cells.
Mechanical stress contributes to vascular disease related to hypertension. Activation of ERK is key to mediating cellular… Expand
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1999
1999
The behavior of calpain-generated N- and C-terminal fragments of talin in integrin-mediated signaling pathways.
Our previous results showed that the binding of an adhesive ligand to integrin alphaIIbbeta(3) on the surface of platelets… Expand
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