inositol 4,5-bisphosphate

Known as: Ins(4,5)P2, myo-inositol 4,5-diphosphate, inositol-4,5-bisphosphate 
 
National Institutes of Health

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Inositol Phosphates

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2010
2010
Selective determinants of inositol 1,4,5-trisphosphate and adenophostin A interactions with type 1 inositol 1,4,5-trisphosphate receptors
BACKGROUND AND PURPOSE Adenophostin A (AdA) is a potent agonist of inositol 1,4,5-trisphosphate receptors (IP(3) R). AdA shares… (More)
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2004
2004
Comparative mechanistic and substrate specificity study of inositol polyphosphate 5-phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2.
Inositol-5-phosphatases are important enzymes involved in the regulation of diverse cellular processes from synaptic vesicle… (More)
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2002
2002
Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor.
Activation of G(q)-coupled alpha(1)-adrenergic receptors leads to hypertrophic growth of neonatal rat ventricular cardiomyocytes… (More)
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2001
2001
Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate.
Using a consensus sequence in inositol phosphate kinase, we have identified and cloned a 44-kDa mammalian inositol phosphate… (More)
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1998
1998
Iron deficiency reduces the hydrolysis of cell membrane phosphatidyl inositol-4,5-bisphosphate during splenic lymphocyte activation in C57BL/6 mice.
Iron deficiency impairs lymphocyte proliferation in humans and laboratory animals by unknown mechanisms. In this study, we… (More)
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1995
1995
Inositol trisphosphate-dependent and -independent Ca2+ mobilization pathways at the vacuolar membrane of Candida albicans.
Vacuolar membrane vesicles were isolated from Candida albicans protoplasts, and marker enzyme assays were employed to identify… (More)
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1992
1992
Evidence for lithium-sensitive inositol 4,5-bisphosphate accumulation in muscarinic cholinoceptor-stimulated cerebral-cortex slices.
Stimulation of [3H]inositol-prelabelled rat cerebral-cortex slices with carbachol results in the accumulation of four [3H… (More)
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1989
1989
Hydrolysis of inositol phosphates by plant cell extracts.
A gel-filtered soluble fraction prepared from suspension-cultured Nicotiana tabacum cells hydrolysed inositol mono-, bis- and… (More)
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1984
1984
Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes.
In permeabilized hepatocytes, inositol 1,4,5-trisphosphate, inositol 2,4,5-trisphosphate and inositol 4,5-bisphosphate induced… (More)
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1984
1984
Specificity of inositol trisphosphate-induced calcium release from permeabilized Swiss-mouse 3T3 cells.
Swiss-mouse 3T3 cells permeabilized with saponin were used to study the specificity of the inositol trisphosphate-induced release… (More)
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