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inositol 4,5-bisphosphate

Known as: Ins(4,5)P2, myo-inositol 4,5-diphosphate, inositol-4,5-bisphosphate 
National Institutes of Health

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Inositol Phosphates

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Highly Cited
2004
Highly Cited
2004
Comparative Mechanistic and Substrate Specificity Study of Inositol Polyphosphate 5-Phosphatase Schizosaccharomyces pombe Synaptojanin and SHIP2*
Inositol-5-phosphatases are important enzymes involved in the regulation of diverse cellular processes from synaptic vesicle… 
Highly Cited
2001
Highly Cited
2001
Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate
Using a consensus sequence in inositol phosphate kinase, we have identified and cloned a 44-kDa mammalian inositol phosphate… 
1998
1998
Iron deficiency reduces the hydrolysis of cell membrane phosphatidyl inositol-4,5-bisphosphate during splenic lymphocyte activation in C57BL/6 mice.
Iron deficiency impairs lymphocyte proliferation in humans and laboratory animals by unknown mechanisms. In this study, we… 
1992
1992
Evidence for lithium-sensitive inositol 4,5-bisphosphate accumulation in muscarinic cholinoceptor-stimulated cerebral-cortex slices.
Stimulation of [3H]inositol-prelabelled rat cerebral-cortex slices with carbachol results in the accumulation of four [3H… 
Highly Cited
1989
Highly Cited
1989
Identification and isolation of a 75-kDa inositol polyphosphate-5-phosphatase from human platelets.
1989
1989
Hydrolysis of inositol phosphates by plant cell extracts.
A gel-filtered soluble fraction prepared from suspension-cultured Nicotiana tabacum cells hydrolysed inositol mono-, bis- and… 
1988
1988
Characterization of inositol 1,4,5-trisphosphate-stimulated calcium release from rat cerebellar microsomal fractions. Comparison with [3H]inositol 1,4,5-trisphosphate binding.
The abilities of D-myo-inositol phosphates (InsPs) to promote Ca2+ release and to compete for D-myo-[3H]-inositol 1,4,5… 
1986
1986
Mammalian aldolases are isomer-selective high-affinity inositol polyphosphate binders.
A search for target proteins of inositol polyphosphates in mammalian tissues revealed that fructose 1,6-bisphosphate aldolases… 
Highly Cited
1984
Highly Cited
1984
Specificity of inositol trisphosphate-induced calcium release from permeabilized Swiss-mouse 3T3 cells.
Swiss-mouse 3T3 cells permeabilized with saponin were used to study the specificity of the inositol trisphosphate-induced release… 
Highly Cited
1984
Highly Cited
1984
Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes.
In permeabilized hepatocytes, inositol 1,4,5-trisphosphate, inositol 2,4,5-trisphosphate and inositol 4,5-bisphosphate induced… 
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