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indanocine

Known as: indanosine 
National Institutes of Health

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Indans

Papers overview

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2009
2009
Binding of indanocine to the colchicine site on tubulin promotes fluorescence, and its binding parameters resemble those of the colchicine analogue AC.
Indanocine, a synthetic indanone, has shown potential antiproliferative activity against several tumor types. It is different… 
2001
2001
Biochemical genetic analysis of indanocine resistance in human leukemia.
Indanocine is a potent tubulin-binding drug that is cytotoxic to multidrug-resistant cancer cell lines. We demonstrated that… 
2001
2001
Mechanism of Action of Substituted Indanones in Multidrug Resistant Breast Cancer
Abstract : Mechanism of Action of Substituted Indanones in Multidrug Resistant Breast Cancer Our laboratory has recently… 
2000
2000
Tubulin as a target for anticancer drugs.
Nature provides a large spectrum of agents that either inhibit the polymerization of tubulin or prevent the disassembly of… 
2000
2000
Understanding apoptosis involved in the development and treatment of malignancies
Apoptosis is a key event occurring in living organisms. In order to maintain tissue homeostasis, a comparable number of cells… 
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