indanocine

Cell motility is an essential aspect of metastatic spread of cancer. Microtubule-targeted agents exhibit anti-metastatic… (More)

Indanocine, a synthetic indanone, has shown potential antiproliferative activity against several tumor types. It is different… (More)

Indanocine is a potent tubulin-binding drug that is cytotoxic to multidrug-resistant cancer cell lines. We demonstrated that… (More)

BACKGROUND Certain antimitotic drugs have antitumor activities that apparently result from interactions with nontubulin… (More)

Most investigators would agree that the ideal chemotherapeutic agent should be 1) directed at a validated target; 2) potent… (More)

Nature provides a large spectrum of agents that either inhibit the polymerization of tubulin or prevent the disassembly of… (More)