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imidazolidin-2-one-4-carboxylate

National Institutes of Health

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BenzoatesImidazolidines

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2008
2008
Synthesis of imidazolidin-2-one-4-carboxylate and of (tetrahydro)pyrimidin-2-one-5-carboxylate via an efficient modification of the Hofmann rearrangement.
A mild and efficient methodology for the rearrangement of protected asparagine and protected glutamine is reported; good results… 
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