ibufenac

Global gene expression profiling is useful for elucidating a drug's mechanism of action on the liver; however, such profiling in… Expand

Xenobiotic carboxylic acids may be metabolized to oxidative metabolites, acyl glucuronides, and/or S-acyl-CoA thioesters (CoA… Expand

Two new structural analogs, 2-(4-hydroxyethoxyphenyl)acetic acid [R3] and 2-(4-hydroxyethoxyphenyl)propionic acid [R4], along… Expand

The rate acceleration of Diels-Alder reactions in 5.0 M lithium perchlorate-diethyl ether was re-examined using itaconic… Expand

The disposition of ibuprofen and ibufenac, an analog of ibuprofen with a history of severe adverse reactions, was investigated in… Expand

Abstract Certain steroidal and nonsteroidal anti-inflammatory drugs were found to stabilize in vitro lysosomes obtained from a… Expand

Summary In cultures of mouse or chick embryo cells several non-steroidal anti-inflammatory drugs (salicylates, Ibufenac… Expand

When given orally to animals ibufenac has a range of potencies 2 to 4 times that of aspirin. It also suppresses thurfyl… Expand

Ibufenac (4-isobutylphenylacetic acid) was reported by Chalmers (1963) to be an effective antirheumatic agent, 1 * 8 g. daily… Expand

Abstract Non-steroid anti-inflammatory acids inhibit two enzymes with broad substrate-specificity for aromatic aminoacid… Expand